ARG-GLY-ASP-SER
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ARG-GLY-ASP-SER
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CAS No:
91037-65-9
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Formula:
C15H27N7O8
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Chemical Name:
ARG-GLY-ASP-SER
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Synonyms:
RGDS;RGDS peptide;ARG-GLY-ASP-SER;L-ARG-GLY-ASP-SER;RGDS 1/2ACOH 2H2O;Arg-Gly-Asp-Ser-OH;H-ARG-GLY-ASP-SER-OH;RGDS/ARG-GLY-ASP-SER;FIBRONECTIN INHIBITOR;L-Arg-Gly-L-Asp-L-Ser-OH
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CAS No:
Description
Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function, decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9.
Drug Information
Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)
Arg-Gly-Asp-Ser
Computed Properties
Molecular Weight:433.42
XLogP3:-7.3
Hydrogen Bond Donor Count:9
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:14
Exact Mass:433.19211085
Monoisotopic Mass:433.19211085
Topological Polar Surface Area:273
Heavy Atom Count:30
Complexity:665
Defined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes