3-Bromo-1-propanol
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3-Bromo-1-propanol
structure -
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CAS No:
627-18-9
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Formula:
C3H7BrO
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Chemical Name:
3-Bromo-1-propanol
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Synonyms:
1-Propanol,3-bromo-;3-Bromo-1-propanol;Trimethylene bromohydrin;3-Hydroxypropyl bromide;1-Bromo-3-propanol;1-Bromo-3-hydroxypropane;3-Bromopropyl alcohol;3-Bromopropane-1-ol
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CAS No:
Description
colourless liquid
3-bromo-1-propanol is a clear colorless liquid. (NTP, 1992)
3-bromo-1-propanol is a clear colorless liquid. (NTP, 1992)|3-Bromo-1-propanol is a primary alcohol.
Characteristics
20.2
0.7
3-bromo-1-propanol is a clear colorless liquid. (NTP, 1992)
1.5374 at 68° F (NTP, 1992)
105 °C
201° F (NTP, 1992)
1.480
H2O: 167 g/L (20 ºC)
2-8ºC
0.13 hPa (20 °C)
Highly flammable. Water soluble.
Alcohols and Polyols
Highly Flammable
3-BROMO-1-PROPANOL may be sensitive to prolonged exposure to light. (NTP, 1992)
Safety Information
NONH for all modes of transport
3
R36/37/38
S26-S39-S37/39
UA7385000
Xi:Irritant
Stable. Incompatible with strong oxidizing agents.
P280-P305 + P351 + P338
H302-H318
This chemical is combustible. (NTP, 1992)
|Danger|H302 (78.43%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 51 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
It is combustible. Fires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this material in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)
MINIMUM PROTECTIVE CLOTHING: If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves. RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. Splash proof safety goggles should be worn while handling this chemical. Alternatively, a full face respirator, equipped as above, may be used to provide simultaneous eye and respiratory protection. RECOMMENDED GLOVE MATERIALS: It is recommended that two different glove types be used for best protection. However, if this chemical makes direct contact with your gloves, or if a tear, puncture or hole develops, remove them at once. SUGGESTED GLOVES: Viton, Butyl rubber, Neoprene, PVA (NTP, 1992)
Drug Information
SYMPTOMS: Related compounds are eye, skin, and mucous membrane irritants and cause severe lung injury if aspirated. ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. Corrosive chemicals will destroy the membranes of the mouth, throat, and esophagus and, in addition, have a high risk of being aspirated into the victim's lungs during vomiting which increases the medical problems. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. Transport the victim IMMEDIATELY to a hospital. (NTP, 1992)
3-Bromo-1-propanol Use and Manufacturing
Structure-mutagenic activity relationships in the Salmonella typhimurium TA100 strain in a series of short-chain halogenated hydrocarbons and alcohols. A reagent used in the synthesis of quaternary chiral prolines
1-Propanol, 3-bromo-: ACTIVE
Computed Properties
Molecular Weight:138.99
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:137.96803
Monoisotopic Mass:137.96803
Topological Polar Surface Area:20.2
Heavy Atom Count:5
Complexity:16.4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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