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8-Methylquinoline

8-Methylquinoline structure

8-Methylquinoline 

structure

Description

clear yellow liquid


8-methylquinoline appears as yellow liquid or oil. (NTP, 1992)


8-methylquinoline appears as yellow liquid or oil. (NTP, 1992)|8-methylquinoline is a methylquinoline carrying a methyl substituent at position 8.

8-Methylquinoline Basic Attributes

143.19

143.19

111340

210-264-0

K97B12J636

9409

DTXSID8020888

29334900

Characteristics

12.9

2.54

Clear yellow Liquid

1.052 g/mL at 25 °C(lit.)

-80 °C

247.5 °C

221 °F

n20/D 1.614(lit.)

H2O: 0.1-0.5 g/100 mL at 17 ºC

5.9 mm Hg at 75° F ; 8.0 mm Hg at 111° F; 12.6 mm Hg at 149° F (NTP, 1992)

Thermal decomposition of toxic nitrogen oxide gas

Slightly soluble in water.

Amines, Phosphines, and Pyridines

8-METHYLQUINOLINE may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Safety Information

IRRITANT

NONH for all modes of transport

3

36/37/38-68-22

26-36-45-36/37/39

VC0562000

Xi,Xn

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

P261-P305 + P351 + P338

H315-H319-H335

This chemical is combustible. (NTP, 1992)

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P201, P202, P261, P264, P271, P280, P281, P302+P352, P304+P340, P305+P351+P338, P308+P313, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 45 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this material from exposure to light, and store it in a refrigerator. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Toxicity

moderately toxic

Drug Information

SYMPTOMS: This compound may be absorbed through the skin and it causes skin irritation. The vapor or mist is irritating to the eyes, mucous membranes and upper respiratory tract. ACUTE/CHRONIC HAZARDS: This compound may be absorbed through the skin. It causes skin irritation. When heated to decomposition it emits toxic fumes. (NTP, 1992)

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

8-methylquinoline

8-Methylquinoline Use and Manufacturing

Uses

Pharmaceutical and pesticide intermediates

Quinoline, 8-methyl-: ACTIVE

Computed Properties

Molecular Weight:143.18
XLogP3:2.6
Hydrogen Bond Acceptor Count:1
Exact Mass:143.073499291
Monoisotopic Mass:143.073499291
Topological Polar Surface Area:12.9
Heavy Atom Count:11
Complexity:133
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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