(2-Methylphenyl)thiourea

166.24

166.24

2086802

210-395-3

4K71RZN35H

5786

2811

DTXSID6060634

Needles (from dilute ethanol, water)

2930909090

70.1

1.19

Thiourea, (2-methylphenyl)- is a crystalline solid. (EPA, 1998)

1.2±0.1 g/cm3

162 °C

275.5±33.0 °C at 760 mmHg

120.4±25.4 °C

1.696

> 10% in ethanol

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

No rapid reaction with air. No rapid reaction with water.

Amides and Imides

When heated to decomposition, it emits very toxic fumes of oxides of nitrogen and sulfur. [EPA, 1998]. Organosulfides are incompatible with acids, diazo and azo compounds, halocarbons, isocyanates, aldehydes, alkali metals, nitrides, hydrides, and other strong reducing agents. Reactions with these materials generate heat and in many cases hydrogen gas. Many of these compounds may liberate hydrogen sulfide upon decomposition or reaction with an acid.

III

6.1

2811

20/21/22-36/37/38

22-26-36/37/39

YU2975000

Xn

P264, P270, P280, P301+P310, P305+P351+P338, P321, P330, P337+P313, P405, P501

H301

USEPA; Chemical Profile: Thiourea, (2-methylphenyl)- (1985)

When heated to decomposition, it emits very toxic fumes of oxides of nitrogen and sulfur. (EPA, 1998)

|Danger|H301 (13.33%): Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P280, P301+P310, P305+P351+P338, P321, P330, P337+P313, P405, and P501|Aggregated GHS information provided by 45 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

(Non-Specific -- Poisonous Solid, n.o.s.) Wear self-contained (positive pressure if available) breathing apparatus and full protective clothing. (Non-Specific -- Poisonous Solid, n.o.s.) For small fires use dry chemical, carbon dioxide, water spray, or foam. Use water spray, fog, or foam on larger fires. Move container from fire area if you can do so without risk. (EPA, 1998)

Excerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]: As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters (150 feet) for liquids and at least 25 meters (75 feet) for solids. SPILL: Increase, in the downwind direction, as necessary, the isolation distance shown above. FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)

(Non-Specific -- Poisonous Solid, n.o.s.) Keep unnecessary people away, isolate hazard area and deny entry. Stay upwind and keep out of low areas. Do not touch spilled material, stop leak if you can do so without risk. Absorb small spills with sand or other noncombustible material and place into containers for later disposal. For large spills, dike far ahead of spill for later disposal. (EPA, 1998)

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Thiourea, (2-methylphenyl)- is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 500/10,000 lbs.

The material is highly toxic if orally ingested. (EPA, 1998)

Warning: Effects may be delayed for up to 72 hours. Caution is advised. Signs and Symptoms of Thiourea, (2-Methylphenyl)- Exposure: No information on specific clinical effects of exposure to thiourea, (2-methylphenyl)- was found in available references. However, signs and symptoms of acute exposure to thiourea, (2-methylphenyl)- may include headaches, dizziness, weakness, nausea, irritation of eyes, skin and respiratory tract. Irritation or burns of the esophagus or gastrointestinal tract are also possible. Emergency Life-Support Procedures: Acute exposure to thiourea, (2-methylphenyl)- may require decontamination and life support for the victims. Emergency personnel should wear protective clothing appropriate to the type and degree of contamination. Air-purifying or supplied-air respiratory equipment should also be worn, as necessary. Rescue vehicles should carry supplies such as plastic sheeting and disposable plastic bags to assist in preventing spread of contamination. Inhalation Exposure: 1. Move victim to fresh air. Emergency personnel should avoid self-exposure to thiourea, (2-methylphenyl)-. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. Monitor for respiratory distress; if cough or difficulty in breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer 100% humidified oxygen to all victims or other respiratory support. 3. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures. 4. Transport to a health care facility. Dermal/Eye Exposure: 1. Remove victims from exposure. Emergency personnel should avoid self-exposure to thiourea, (2-methylphenyl)-. 2. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. Monitor for respiratory distress; if cough or difficulty in breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer 100% humidified oxygen to all victims or other respiratory support. 3. Remove contaminated clothing as soon as possible. 4. If eye exposure has occurred, eyes must be flushed with lukewarm water for at least 15 minutes. 5. Wash exposed skin areas thoroughly with soap and water. 6. Obtain authorization and/or further instructions from the local hospital for performance of other invasive procedures. 7. Transport to a health care facility. Ingestion Exposure: 1. Evaluate vital signs including pulse and respiratory rate, and note any trauma. If no pulse is detected, provide CPR. If not breathing, provide artificial respiration. If breathing is labored, administer 100% humidified oxygen or other respiratory support. 2. Obtain authorization and/or further instructions from the local hospital for administration of an antidote or performance of other invasive procedures. 3. Transport to a health care facility. (EPA, 1998)

In the manufacture of rubber, irritant contact dermatitis may occur from a variety of acids, alkalies, detergents, and solvents used in the process. Allergic contact dermatitis occurs not infrequently and is almost always due to an organic accelerator or antioxidant. While the list of potential sensitizing accelerators and antioxidants is enormous, common allergens include ... thioureas. /Thioureas/

Thiourea, N-(2-methylphenyl)-: ACTIVE