Desonide
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Desonide
structure -
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CAS No:
638-94-8
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Formula:
C24H32O6
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Chemical Name:
Desonide
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Synonyms:
Pregna-1,4-diene-3,20-dione,11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(11β,16α)-;Pregna-1,4-diene-3,20-dione,11β,16α,17,21-tetrahydroxy-,cyclic 16,17-acetal with acetone;2H-Naphth[2′,1′:4,5]indeno[1,2-d][1,3]dioxole,pregna-1,4-diene-3,20-dione deriv.;(11β,16α)-11,21-Dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione;16α-Hydroxyprednisolone 16α,17α-acetonide;Desonide;Prednacinolone;16α-Hydroxyprednisolone acetonide;11β,16α,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione 16,17-acetonide;Tridesilon;16α-Hydroxyprednisolone 16,17-acetonide;16α,17α-(Isopropylidenedioxy)prednisolone;Steroderm;11β,21-Dihydroxy-16α,17α-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione;Prednacinolone acetonide;Apolar;D 2083;Locapred;Topifug;Sterax;Budesonide acetonide;Prenacid;Tridesonit;Prednisolone acetonide;Desowen;24814-50-4;63905-08-8
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CAS No:
Description
Desonide is a nonfluorinated corticosteroid anti-inflammatory agent used topically for dermatoses.Target: Glucocorticoid ReceptorDesonide is a low-potency topical corticosteroid that has been used for decades in the treatment of steroid-responsive dermatoses [1]. Desonide induced significant colorimetric improvement compared with placebo. A good to excellent response was achieved in 30% for desonide, and 6% for placebo. Decreased pigmentation in the desonide-treated axillae was associate
Characteristics
93.06000
2.32670
Powder
1.3 g/cm3
274 °C
580.1ºC at 760 mmHg
196.9ºC
1.598
Refrigerator
LD50 in rats (mg/kg): 93 s.c. (Phillips)
Drug Function and Efficacy
This product is a glucocorticoid drug with anti-inflammatory, anti-allergic, antipruritic and exudation-reducing effects; it can reduce and prevent tissue response to inflammation, eliminate fever, redness and swelling caused by local non-infectious inflammation, thereby reducing the manifestations of inflammation; it has an immunosuppressive effect of preventing or inhibiting cellular immune responses and suppressing primary immune responses.
Registered Holders
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AARTI PHARMALABS LTD
Active
United States
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TAPI NL B.V.
Active
France
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Chongqing Shengkai Pharmaceutical Co., Ltd.
Active
China
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