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D-Valine

D-Valine structure

D-Valine 

structure
  • CAS No:

    640-68-6

  • Formula:

    C5H11NO2

  • Chemical Name:

    D-Valine

  • Synonyms:

    D-Valine;Valine,D-;(R)-Valine;D-(-)-Valine;NSC 20654;(-)-2-Amino-3-methylbutyric acid;(R)-3-Methyl-2-aminobutanoic acid;(R)-2-Amino-3-methylbutanoic acid;(R)-2-Amino-3-methylbutanoic acid;(2R)-2-Amino-3-methylbutanoic acid

  • Categories:

    Cosmetic Ingredient  >  Antistatic

Description

White crystal, m.p.> 295 °C (sublimation), [α] 25 = 27.35°; it is soluble in water and very slightly soluble in ethanol. white to off-white crystalline powder


D-valine is the D-enantiomer of valine. It is a valine and a D-alpha-amino acid. It is a conjugate base of a D-valinium. It is a conjugate acid of a D-valinate. It is an enantiomer of a L-valine. It is a tautomer of a D-valine zwitterion.

D-Valine Basic Attributes

117.14600

117.15

211-368-9

Y14I1443UR

DTXSID0046064

29224995

Characteristics

63.32000

-2.3

white crystals

1.063 g/cm3

280 °C

213.6ºC at 760 mmHg

83ºC

-27 ° (C=8, 6mol/L HCl)

H2O: 56 g/L (20 ºC)

Store at RT.

Safety Information

NONH for all modes of transport

3

R36/37/38

S22-S24/25

YV9360000

Xi

Stable under normal shipping and handling conditions.

D-Valine Use and Manufacturing

Uses

D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase. D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats.

D-Valine: ACTIVE

Computed Properties

Molecular Weight:117.15
XLogP3:-2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:117.078978594
Monoisotopic Mass:117.078978594
Topological Polar Surface Area:63.3
Heavy Atom Count:8
Complexity:90.4
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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