D-Valine
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D-Valine
structure -
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CAS No:
640-68-6
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Formula:
C5H11NO2
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Chemical Name:
D-Valine
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Synonyms:
D-Valine;Valine,D-;(R)-Valine;D-(-)-Valine;NSC 20654;(-)-2-Amino-3-methylbutyric acid;(R)-3-Methyl-2-aminobutanoic acid;(R)-2-Amino-3-methylbutanoic acid;(R)-2-Amino-3-methylbutanoic acid;(2R)-2-Amino-3-methylbutanoic acid
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CAS No:
Description
White crystal, m.p.> 295 °C (sublimation), [α] 25 = 27.35°; it is soluble in water and very slightly soluble in ethanol. white to off-white crystalline powder
D-valine is the D-enantiomer of valine. It is a valine and a D-alpha-amino acid. It is a conjugate base of a D-valinium. It is a conjugate acid of a D-valinate. It is an enantiomer of a L-valine. It is a tautomer of a D-valine zwitterion.
Characteristics
63.32000
-2.3
white crystals
1.063 g/cm3
280 °C
213.6ºC at 760 mmHg
83ºC
-27 ° (C=8, 6mol/L HCl)
H2O: 56 g/L (20 ºC)
Store at RT.
Safety Information
NONH for all modes of transport
3
R36/37/38
S22-S24/25
YV9360000
Xi
Stable under normal shipping and handling conditions.
D-Valine Use and Manufacturing
D-Valine is an isomer of the essential amino acid L-Valine. D-Valine has been used as a selective agent in epithelial cells in culture since it inhibits cells that lack the enzyme D-amino acid oxidase. D-Valine has also been shown to inhibit proliferation of contaminating fibroblasts in smooth muscle cells from human myometrium. D-Valine solution showed tumor growth inhibition and improvements of the nutritional status in AH109A hepatoma-bearing rats.
D-Valine: ACTIVE
Computed Properties
Molecular Weight:117.15
XLogP3:-2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:117.078978594
Monoisotopic Mass:117.078978594
Topological Polar Surface Area:63.3
Heavy Atom Count:8
Complexity:90.4
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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