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Home > Encyclopedia > 2-Fluoro-6-Methoxynitrobenzene

2-Fluoro-6-Methoxynitrobenzene

2-Fluoro-6-Methoxynitrobenzene structure

2-Fluoro-6-Methoxynitrobenzene 

structure
  • CAS No:

    641-49-6

  • Formula:

    C7H6FNO3

  • Chemical Name:

    2-Fluoro-6-Methoxynitrobenzene

  • Synonyms:

    3-Fluoro-2-nitroanisole;1-fluoro-3-methoxy-2-nitrobenzene;2-FLUORO-6-METHOXYNITROBENZENE;1-fluoro-3-methoxy-2-nitro-benzene;Benzene, 1-fluoro-3-methoxy-2-nitro-;3-Fluoro-2-nitroanisol;ACMC-1B4OV;SCHEMBL6117;KSC307C0P;2-fluoro-6-methoxy-nitrobenzene

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

2-Fluoro-6-Methoxynitrobenzene Basic Attributes

171.13

171.033173

DTXSID70382284

2909309090

Characteristics

55

1.8

1.3±0.1 g/cm3

107.4±21.8 °C

1.522

Safety Information

2811

6.1

2-Fluoro-6-Methoxynitrobenzene Use and Manufacturing

To a solution of 2, 6-difluoronitrobenzene (5 g, 32 mmol) in methanol (50 mL) was added potassium hydroxide (1.8 g, 32.5 mmol), and the mixture was heated to reflux for 3 hr. Water was added, and the mixture was extracted with dichloromethane. The organic layer was separated, dried, filtered, and evaporated to yield 5.1 g (95percent) of 1-fluoro-3-methoxy-2-nitrobenzene, 1e. MS m/z (MH

Computed Properties

Molecular Weight:171.13
XLogP3:1.8
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:171.03317122
Monoisotopic Mass:171.03317122
Topological Polar Surface Area:55
Heavy Atom Count:12
Complexity:171
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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