TETRAHYDROPALMATINE HYDROCHLORIDE
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TETRAHYDROPALMATINE HYDROCHLORIDE
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CAS No:
6024-85-7
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Formula:
C21H26ClNO4
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Chemical Name:
TETRAHYDROPALMATINE HYDROCHLORIDE
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Synonyms:
(D,L)-TETRAHYDROPALMATINE HYDROCHLORIDE;TETRAHYDROPALMATINE HYDROCHLORIDE;SALOR-INT L202088-1EA;2,3,9,10-tetramethoxy-,hydrochloride,(+-)-berbin;Tetrahydropalmatine Sulfate 6024-85-7;tetrahydro-,hydrochloride,(+-)-palmatin;Tetrahydropalmatine, HCl;corydalis B
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CAS No:
Description
Tetrahydropalmatine hydrochloride (DL-Tetrahydropalmatine hydrochloride), an active component isolated from corydalis, possesses analgesic effects. Tetrahydropalmatine hydrochloride acts through inhibition of amygdaloid release of dopamine to inhibit an epileptic attack in rats[1].
TETRAHYDROPALMATINE HYDROCHLORIDE Use and Manufacturing
Hydrochloride salt of DL-Tetrahydropalmatine is the main active substance of the Chinese herb corydalis which induces hypotension and bradycardia in rats through the antagonism of striatal dopamine D2 receptor.
Computed Properties
Molecular Weight:391.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:391.1550360
Monoisotopic Mass:391.1550360
Topological Polar Surface Area:41.4
Heavy Atom Count:27
Complexity:475
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Non-narcotic analgesics, with analgesic, sedative, sleep-inducing and tranquilizing effects, especially effective for dull pain caused by the gastrointestinal system
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TETRAHYDROPALMATINE HYDROCHLORIDE
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