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Triprolidine hydrochloride monohydrate

Triprolidine hydrochloride monohydrate structure

CAS No:
6138-79-0
Formula:
C19H22N2.ClH.H2O
Chemical Name:
Triprolidine hydrochloride monohydrate
Synonyms:
Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-,hydrochloride,hydrate (1:1:1);Pyridine,2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,monohydrochloride,monohydrate,stereoisomer;Pyridine,2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-,monohydrochloride,monohydrate,(E)-;Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-,monohydrochloride,monohydrate;Triprolidine hydrochloride monohydrate
Categories:
Active Pharmaceutical Ingredients > Antiallergic Drugs

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Description

TRIPROLIDINE HYDROCHLORIDE is a white, crystalline powder.

Triprolidine hydrochloride monohydrate Basic Attributes

Molecular Weight：

314.85

Exact Mass：

314.15500

HScode：

2933399090

Characteristics

PSA：

17.1

Appearance：

Triprolidine hydrochloride monohydrate is an odorless white crystalline powder. Bitter taste. (NTP, 1992)

Melting Point：

115-120°C

Boiling Point：

435.4°C at 760 mmHg

Flash Point：

233.2ºC

Water Solubility：

H2O: >=10 g/100 mL at 20 ºC;alcohol: soluble 1 in 1.5 of solvent

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

22-36/37/38

safety instructions：

26-36

RTECS Number：

UT7658000

Marks：

Stability/Shelf Life：

Stable, but discolours in light. Incompatible with strong oxidizing agents.

Precautionary statement(s)：

P301 + P312 + P330-P305 + P351 + P338

Hazard Statements：

H302-H315-H319-H335

Triprolidine hydrochloride monohydrate Use and Manufacturing

anticholinergic (opthalmic)

Drug Function and Efficacy

A potent H receptor antagonist with central sedative and anti-muscarinic effects, it eliminates allergic reactions caused by histamine by competitively and reversibly blocking histamine receptors on tissues.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound Pholcodine Oral Solution
Ingredients	Pholcodine, triprolidine hydrochloride, pseudoephedrine hydrochloride, guaiacol glyceryl ether, onion fluid extract, polygala fluid extract, flavoring, preservative, distilled water
Indication	1. Combination with monoamine oxidase inhibitors may increase blood pressure. 2. Avoid combination with other sympathomimetics, such as decongestants, appetite suppressants, amphetamines, antihypertensives and other antihistamines.
Specifications	Each 5 ml contains 5.0 mg of pholcodine, 0.6 mg of triprolidine hydrochloride, 15.0 mg of pseudoephedrine hydrochloride and 50.0 mg of guaiacol glycerol ether.

Aminophene and quinamine tablets
Ingredients	This product is a compound preparation, each tablet contains 200 mg of acetaminophen, 100 mg of salicylamide, 15 mg of caffeine, 30 mg of pseudoephedrine hydrochloride, and 1.2 mg of triprolidine hydrochloride. Excipients are: microcrystalline cellulose, low-substituted hydroxypropyl cellulose, hypromellose, micro-powdered silica gel, talc, magnesium stearate, ethyl cellulose, and titanium dioxide.
Indication	1. This product should not be taken at the same time as antihypertensive drugs or antidepressants. 2. If used at the same time with other drugs, drug interactions may occur. Please consult a physician or pharmacist for details.
Specifications	Compound
Manufacturer	Zhuhai United Pharmaceutical Co., Ltd. Zhongshan Branch

Triprolidine hydrochloride
Manufacturer	Zhuhai UNITED Laboratories Co., Ltd.

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Registered Holders

MALLADI DRUGS AND PHARMACEUTICALS LTD

United States
Active
HIKAL LTD

United States
Active
Zhao QING City Dingkang Pharmaceutical Co., Ltd.

China
Active

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

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Triprolidine hydrochloride

CAS No.: 6138-79-0

Content: 99.00%

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Shaanxi Dideu Medichem Co. Ltd Contact Supplier

CN
5 YRS

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Triprolidine hydrochloride 99% Dideu-5-00472 Dideu

CAS No.: 6138-79-0

Grade: Pharmaceutical Grade

Content: 99%

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Guide of Triprolidine hydrochloride monohydrate

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
Learn More Other Chemicals

Triprolidine hydrochloride monohydrate

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