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1-Chloro-4-nitrobenzene

1-Chloro-4-nitrobenzene structure

CAS No:
100-00-5
Formula:
C6H4ClNO2
Chemical Name:
1-Chloro-4-nitrobenzene
Synonyms:
Benzene,1-chloro-4-nitro-;1-Chloro-4-nitrobenzene;p-Chloronitrobenzene;4-Chloro-1-nitrobenzene;p-Nitrochlorobenzene;PNCB;p-Nitrophenyl chloride;4-Chloronitrobenzene;4-Nitrochlorobenzene;4-Nitro-1-chlorobenzene;1-Nitro-4-chlorobenzene;4-Nitrophenyl chloride;NSC 9792
Categories:
Organic Chemistry > Hydrocarbons and Derivatives

Description

Yellow, crystalline solid with a sweet odor.

4-Nitrochlorobenzene is the organic compound with the formula ClC6H4NO2. It is a pale yellow solid. 4-Nitrochlorobenzene is a common intermediate in the production of a number of industrially useful compounds, including common antioxidants found in rubber. Other isomers with the formula ClC6H4NO2 include 2-nitrochlorobenzene and 3-nitrochlorobenzene.

1-Chloro-4-nitrobenzene Basic Attributes

Molecular Weight：

157.55400

Exact Mass：

157.55

EC Number：

202-809-6

HScode：

29049085

Characteristics

PSA：

45.82000

XLogP3：

2.77140

Appearance：

P-nitrochlorobenzene is a light yellow crystalline solid. Density 1.520 g / cm3. Melting point 83°C. Sweet odor. Very toxic by inhalation, ingestion, and skin absorption.

Density：

1.520 g/cm³

Melting Point：

82-84 °C

Boiling Point：

242 °C @ Press: 760 Torr

Flash Point：

127ºC

Refractive Index：

1.5376 (100ºC)

Water Solubility：

H2O: Insoluble

Storage Conditions：

Store in a cool, dry place. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep containers tightl

Vapor Pressure：

0.09 mm Hg ( 25 °C)

Vapor Density：

5.4 (vs air)

Flammability characteristics：

Solid that does not burn, or burns with difficulty.

Odor：

Sweet odor

Safety Information

Packing level：

Hazard category：

6.1

Transport codes：

UN 1578

wgk germany：

hazard class code：

R23/24/25; R40; R48/20/21/22; R51/53; R68

safety instructions：

S28-S36/37-S45-S61

RTECS Number：

CZ1050000

Marks：

Storage features：

Separated from combustible substances, reducing agents and food and feedstuffs. Keep in a well-ventilated room.

Stability/Shelf Life：

Stable. Combustible. Incompatible with strong oxidizing agents, hydroxides. Reacts violently with sodium methoxide in methanol.

Precautionary statement(s)：

P261-P273-P280-P301 + P310-P311

Hazard Statements：

H301-H311-H331-H341-H351-H373-H411

RIDADR：

UN 1578

Toxicity

Name	Type of Test	Exposure Route	Species Observed	Dose/Duration	Toxic Effects	Reference
ACUTE TOXICITY DATA	LD50 - Lethal dose, 50 percent kill	Oral	Rodent - rat	420 mg/kg	Behavioral--somnolence (general depressed activity) Liver--fatty liver degeneration Blood--methemoglobinemia-carboxyhemoglobin	Archiv fuer Gewerbepathologie und Gewerbehygiene. (Berlin, Ger.) V.1-18, 1930-61. For publisher information, see IAEHDW. Volume(issue)/page/year: 17,217,1959
ACUTE TOXICITY DATA	LCLo - Lowest published lethal concentration	Inhalation	Rodent - rat	16100 mg/m3/4H	Details of toxic effects not reported other than lethal dose value--	Documentation of the Threshold Limit Values and Biological Exposure Indices, 5th ed., Cincinnati, OH, American Conference of Governmental Industrial Hygienists, Inc., 1986 Volume(issue)/page/year: 6,1100,1991
ACUTE TOXICITY DATA	LD50 - Lethal dose, 50 percent kill	Administration onto the skin	Rodent - rat	16 gm/kg	Behavioral--food intake (animal) Kidney, Ureter, Bladder--changes in tubules (including acute renal failure, acute tubular necrosis) Blood--methemoglobinemia-carboxyhemoglobin	Archiv fuer Gewerbepathologie und Gewerbehygiene. (Berlin, Ger.) V.1-18, 1930-61. For publisher information, see IAEHDW. Volume(issue)/page/year: 17,217,1959

1-Chloro-4-nitrobenzene Use and Manufacturing

Computed Properties

Molecular Weight:157.55
XLogP3:2.4
Hydrogen Bond Acceptor Count:2
Exact Mass:156.9930561
Monoisotopic Mass:156.9930561
Topological Polar Surface Area:45.8
Heavy Atom Count:10
Complexity:126
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Synthesis Route

7227-92-1

353253-63-1

Material

4-Chloroaniline

Chlorobenzene

Sodium hydroxide

Sulfuric acid

Nitric acid

Downstream Products

4-Chloroaniline

Albendazole

Norfloxacin

2-Chloro-5-nitrobenzenesulfonic acid

Price Analysis

Make your 1-Chloro-4-nitrobenzene purchase based on the price and market insights! ECHEMI provides professional market insights with prices for you to make a better choice. Learn more on 1-Chloro-4-nitrobenzene prices .

Data: 2026-05-11
Price: 13000.00Yuan/mt
Change: 8700.0

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