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Bacitracin Zinc

Bacitracin Zinc structure

CAS No:
1405-89-6
Formula:
C66H101N17O16SZn
Chemical Name:
Bacitracin Zinc
Synonyms:
(4R)-4-[(2S)-2-({2-[(1S)-1-amino-2-methylbutyl]- 4,5-dihydro-1,3-thiazol-5-yl}formamido)-4-methylpentanamido]-4-{[(1S)- 1-{[(3S,6R,9S,12R,15S,18R,21S)- 18-(3-aminopropyl)-12-benzyl-15-(butan-2-yl)-3-(carbamoylmethyl)- 6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-2,5,8,11,14,17,20- heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl]carbamoyl}- 2-methylbutyl]carbamoyl}butanoic acid mono zinc salt;Zinc(II) (R)-5-(((2S,3S)-1-(((3S,6R,9S,12R,15S,18R,21S)-9-((1H-imidazol-5-yl)methyl)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-12-benzyl-15-((S)-sec-butyl)-6-(carboxylatomethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclopentacosan-21-yl)amino)-3-methyl-1-oxopentan-2-yl)amino)-4-((S)-2-((S)-2-((1S,2S)-1-amino-2-methylbutyl)-4,5-dihydrothiazole-5-carboxamido)-4-methylpentanamido)-5-oxopentanoate;;8028-08-8;8028-35-1;8058-81-9;11031-59-7;73560-74-4;92528-87-5
Categories:
Active Pharmaceutical Ingredients > Antibiotics

Description

Bacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.Target: AntibacterialBacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-t

Bacitracin is a peptide antibiotic effective against gram-postive bacteria. Bacitracin is an inhibitor of peptidoglycan synthesis. Bacitracin disrupts bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Bacitracin also strongly inhibits proline endopeptidase from human muscle.

Bacitracin Zinc Basic Attributes

Molecular Weight：

1486.06994628906

Exact Mass：

1485.677002

EC Number：

215-787-8

Characteristics

PSA：

561.83000

XLogP3：

1.05220

Appearance：

White to light yellow-gray or beige Fine Crystalline Powder

Melting Point：

250 °C (dec.)

Water Solubility：

H2O: 5.1 g/L (28 ºC)

Storage Conditions：

2-8°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

22-24/25

Bacitracin Zinc Use and Manufacturing

Bacitracin zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.

Drug Function and Efficacy

First aid antibiotic

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

LARGE ANSI FIRST AID KIT- water, benzalkonium chloride, isopropyl alcohol, bacitracin zinc, neomycin sulfate, polymyxin b sulfate, lidocaine hydrochloride
Manufacturer	CMC Group, Inc.

CARE BUS AND CLASSROOM YELLOW- bacitracin zinc, neomycin sulfate, polymyxin b sulfate, benzalkonium chloride, lidocaine hydrochloride, isopropyl alcohol, benzocaine, alcohol
Manufacturer	CMC Group, Inc.

STANDARD ANSI FIRST AID- water, benzalkonium chloride, isopropyl alcohol, bacitracin zinc, neomycin sulfate, polymyxin b sulfate, lidocaine hydrochloride
Manufacturer	CMC Group, Inc.

See More Related Drugs

Registered Holders

XELLIA PHARMACEUTICALS ApS

Denmark
Active
ALP PHARM BEIJING CO LTD

United States
Active
SIGMA F AND D DIV LTD

United States
Inactive

See More Registered Holders

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