Tocopherols
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Tocopherols
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CAS No:
1406-66-2
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Chemical Name:
Tocopherols
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Synonyms:
Tocopherols;Tocopherol;Rikki N 70;Covi-Ox T 50;E-Mix 80;E-Mix 40A;Covi-Ox T 30P;Tenox GT;Controx VP;Golden Tocopherol 70;Dry E-Mix 20;E-Mix P 20;E-Oil 600;Irganox E 217DF;E-Oil 800;E-Oil 700;E-Mix 60;Covi-Ox T 70;E 306;E-Oil 705;CoviOx;Tocomix L 70;Riken Oil Super 80;Oxynat 70IP;Copherol F 1300;Riken E Oil Super 80G;Decanox MTS 50;Riken E-Oil 710;Riken E-Oil Super 80;Tocovet E 1000;Tocovet M 90;Tocovet;Covi-ox T 90;E-Oil 805D;AT 160;E-Oil Super 60;BK 801;Tokomikkusu 500;Grindox 497;Fortium MTD 10;Riken E-Emulsion;Riken Dry E-Mix SP-T;Covi-Ox T 7OC;Riken E-Oil 705;Riken E-Oil Super 60;Covi-Ox T 90EU-C;MTS 60S;E-Mix 35L;Tocoblend L 50IP;Riken E Oil 700;Tocolit Powder 30;Riken E Oil 600N;Tocopherol 80;146814-15-5;188763-17-9
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CAS No:
Description
Pale yellow, viscous liquid.
Alpha-tocopherol is a pale yellow, viscous liquid. (NTP, 1992)
Alpha-tocopherol is a pale yellow, viscous liquid. (NTP, 1992)|A collective name for a group of closely related lipids that contain substitutions on the 2H-1-benzopyran-6-ol nucleus and a long hydrocarbon chain of isoprenoid units. They are antioxidants by virtue of the phenolic hydrogen. Tocopherols react with the most reactive form of oxygen and protect unsaturated fatty acids from oxidation.
Characteristics
29.46000
8.84020
Alpha-tocopherol is a pale yellow, viscous liquid. (NTP, 1992)
0.930 g/mL at 25 °C
36.5 to 38.3 °F (NTP, 1992)
>200°C
>200℃
n20/D1.501
Insoluble in water.
Insoluble in water.
Alcohols and Polyols
ALPHA-TOCOPHEROL is stable to heat and alkalis in the presence of oxygen, and is not affected by acids up to 212° F. It is slowly oxidized by atmospheric oxygen and rapidly oxidized by ferric and silver salts. It gradually darkens on exposure to light. (NTP, 1992).
Safety Information
NONH for all modes of transport
1
Flash point data for this compound are unavailable, but it is probably combustible. (NTP, 1992)
Fires involving this compound should be controlled using a Halon, carbon dioxide, or dry chemical extinguisher. (NTP, 1992)
SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with acetone followed by washing with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should protect this chemical from exposure to light. Keep the container tightly closed under an inert atmosphere, and store under refrigerated temperatures. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
Organic substances that are required in small amounts for maintenance and growth, but which cannot be manufactured by the human body. (See all compounds classified as Vitamins.)|Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Abortosan
Tocopherols Use and Manufacturing
2H-1-Benzopyran-6-ol, 3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-: ACTIVE
Computed Properties
Molecular Weight:416.7
XLogP3:10.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:12
Exact Mass:416.365430770
Monoisotopic Mass:416.365430770
Topological Polar Surface Area:29.5
Heavy Atom Count:30
Complexity:475
Undefined Atom Stereocenter Count:3
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Acts as an antioxidant, protects the skin from oxidative damage, and delays skin aging
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