4,4′-Dinitro-1,1′-biphenyl

244.206

244.20

216-210-2

6X8N704C9U

8738

DTXSID4061757

NEEDLES FROM ALCOHOL

2904209090

91.6

3.21

1.3468 (rough estimate)

240-243 °C

387.12°C (rough estimate)

208.8±14.6 °C

1.6360 (estimate)

INSOL IN WATER; SOL IN HOT ALCOHOL, BENZENE & ACETIC ACID

2.74e-08 mmHg

UV: 2-287 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Biphenyl, 2,4'-dinitro/|UV: 2-287 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Biphenyl, 3,3'-dinitro/|UV: 2-287 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Biphenyl, 3,4'dinitro/

R20/21/22

22-36/37/39

DV4000000

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P312, P322, P330, P363, P501

H302

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

FOLLOWING THE ORAL OR IP ADMIN OF 4,4'-DINITROBIPHENYL TO GUINEA PIGS, 4,4'-DIACETYLBENZIDINE (4,4'-DIACETYLAMINOBIPHENYL) WAS EXCRETED IN THE URINE. THE METABOLISM OF 4,4'-DINITROBIPHENYL IN THE RAT WAS CONSIDERABLY SLOWER THAN IN THE GUINEA PIG. 3-CHLORO-4-AMINO-4'-NITROBIPHENYL & 3-CHLORO-4-ACETAMIDO-4'-NITROBIPHENYL WERE FOUND IN THE URINE OF RATS BUT NOT OF GUINEA PIGS. APPARENTLY, IN THE RAT HALOGENATION OCCURS IN A METABOLIC PATHWAY FOR THE METABOLITES OF 4,4'-DINITROBIPHENYL, 4-AMINO-4'-NITROBIPHENYL & 4-ACETAMIDO-4'-NITROBIPHENYL.

4,4'-dinitrobiphenyl

1,1'-Biphenyl, 4,4'-dinitro-: INACTIVE

THE HIGH-PRESSURE LIQUID CHROMATOGRAPHIC ANALYSIS OF A SERIES OF BIPHENYLS SUBSTITUTED AT POSITIONS 2-, 3-, 4-, 4,4'- & 3,4-, KNOWN OR SUSPECTED CARCINOGENS, WAS CARRIED OUT IN THE 3 COMMON MODES: ADSORPTION, NORMAL PARTITION & REVERSED-PHASE PARTITION. UV ABSORPTION MONITORING OF THE EFFLUENT WAS USED AS THE METHOD OF DETECTION.|DETERMINATION OF AROMATIC NITRO COMPD IN AIRBORNE PARTICULATES BY GAS CHROMATOGRAPHY.

BIPHENYL DERIVATIVES COULD BE DETERMINED QUANTITATIVELY BY A COMBINATION OF THIN-LAYER CHROMATOGRAPHY AND PHOTODENSITOMETRY. IN THIS MANNER IT WAS POSSIBLE TO DETECT URINARY METABOLITES OF 4,4'-DINITROBIPHENYL.