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2-Bromo-2-methylpropionic acid

2-Bromo-2-methylpropionic acid structure

CAS No:
2052-01-9
Formula:
C4H7BrO2
Chemical Name:
2-Bromo-2-methylpropionic acid
Synonyms:
2-BROMO-2-METHYLPROPIONIC ACID;2-bromo-2-methyl-propanoicaci;2-bromo-2-methyl-Propanoicacid;Isobromobutyric acid;Propanoic acid, 2-bromo-2-methyl-;Propionic acid, 2-bromo-2-methyl-;a-Bromo-#niso-butyric acid;2-BROMOISOBUTYRIC ACID(2-BROMO-2-METHYLPROPIONIC ACID)
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

white powder

The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

2-Bromo-2-methylpropionic acid Basic Attributes

Molecular Weight：

167

Exact Mass：

167.00

BRN：

1745543

EC Number：

218-139-2

UNII：

821P2R6B0A

NSC Number：

41213

TSCA：

TSCA listed

DSSTox ID：

DTXSID8062151

Color/Form：

Clear colorless to slightly yellow

HScode：

29156000

Characteristics

PSA：

37.30000

XLogP3：

1.20

Appearance：

white powder

Density：

1.43 g/cm3

Melting Point：

44-47 °C(lit.)

Boiling Point：

198-200 °C(lit.)

Flash Point：

78.8±19.8 °C

Refractive Index：

1.4570 (estimate)

Water Solubility：

Soluble in alcohol and ether. Slightly soluble in water.

Vapor Pressure：

0.147mmHg at 25°C

PKA：

2.91±0.10(Predicted)

Critical Temperature & Pressure：

under inert gas (nitrogen or Argon) at 2–8 °C

Safety Information

Packing level：

III

Hazard category：

Transport codes：

UN 3261 8/PG 2

wgk germany：

hazard class code：

safety instructions：

26-36/37/39-45-25

Marks：

C:Corrosive;

Stability/Shelf Life：

Stable. Incompatible with strong oxidizing agents, strong bases.

Precautionary statement(s)：

P280-P305 + P351 + P338-P310

Hazard Statements：

RIDADR：

UN 3261 8/PG 2

GHS Classification：

|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501|Aggregated GHS information provided by 51 companies from 6 notifications to the ECHA C&L Inventory.

2-Bromo-2-methylpropionic acid Use and Manufacturing

Uses

2-Bromo-2-methylpropionic acid is used in the Herceptin functionalization of polyhedral oligomeric silsesquioxane-conjugated oligomers-silica /iron oxide nanoparticles for tumor cell sorting.

2-Bromoisobutyric acid is used in the synthesis of dextran macroinitiator for atom transfer radical polymerization (ATRP) by partial esterification of hydroxyl group of the polysaccharide. The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

Manufacturing Info：

Propanoic acid, 2-bromo-2-methyl-: ACTIVE

Computed Properties

Molecular Weight:167.00
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:165.96294
Monoisotopic Mass:165.96294
Topological Polar Surface Area:37.3
Heavy Atom Count:7
Complexity:87.7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2-Bromo-2-methylpropionic acid

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2-Bromo-2-methylpropionic acid

CAS No.: 2052-01-9

Content: 99.00%

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Greenbo Biochem Contact Supplier

CN
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2-Bromo-2-methylpropionic acid 99% high purity certified Professional producer Greenbo

CAS No.: 2052-01-9

Grade: Industrial Grade

Content: 99%

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Guide of 2-Bromo-2-methylpropionic acid

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Recommended Suppliers
Latest News
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2-Bromo-2-methylpropionic acid

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