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Sulfaclozine

Sulfaclozine structure

CAS No:
102-65-8
Formula:
C10H9ClN4O2S
Chemical Name:
Sulfaclozine
Synonyms:
Benzenesulfonamide,4-amino-N-(6-chloro-2-pyrazinyl)-;Benzenesulfonamide,4-amino-N-(6-chloropyrazinyl)-;Sulfanilamide,N1-(6-chloropyrazinyl)-;4-Amino-N-(6-chloro-2-pyrazinyl)benzenesulfonamide;N1-(6-Chloropyrazinyl)sulfanilamide;Esb3;Sulfatyf;Sulfaclozine;Esb3 (antibiotic);Sulfachloropyrazine;27890-59-1
Categories:
Active Pharmaceutical Ingredients > Antiparasitic Drugs

Description

Sulfaclozine is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects.Target: Antibacterial, AntiparasiticSulfaclozine is an antibiotic commonly used in poultry for the treatment of coccidiosis and various infectious diseases, in broiler chickens. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).

Sulfaclozine Basic Attributes

Molecular Weight：

284.72

Exact Mass：

284.72

EC Number：

203-044-0

UNII：

69YP7Z48CW

DSSTox ID：

DTXSID60144515

HScode：

2935009090

Characteristics

PSA：

106

XLogP3：

0.9

Appearance：

Slightly yellow crystal powder

Density：

1.6±0.1 g/cm3

Melting Point：

234.8-235.4 °C

Boiling Point：

495.7°C at 760 mmHg

Flash Point：

253.6±31.5 °C

Refractive Index：

1.683

Drug Information

MeSH Entry Terms：

Esb-3

Sulfaclozine Use and Manufacturing

Sulfonamide antibacterials, used for the infection of Escherichia coli and Bacillus of livestock and poultry. Compounded with trimethoprim and sucrose, the compound sulfachloropyridazine sodium salt is more effective. Those who are allergic to sulfonamides are contraindicated, and those with impaired renal function Use with caution.

Computed Properties

Molecular Weight:284.72
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:284.0134744
Monoisotopic Mass:284.0134744
Topological Polar Surface Area:106
Heavy Atom Count:18
Complexity:365
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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