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Xanthotoxol

Xanthotoxol structure

CAS No:
2009-24-7
Formula:
C11H6O4
Chemical Name:
Xanthotoxol
Synonyms:
7H-Furo[3,2-g][1]benzopyran-7-one,9-hydroxy-;Xanthotoxol;5-Benzofuranacrylic acid,6,7-dihydroxy-,δ-lactone;9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one;Psoralen,8-hydroxy-;2-Propenoic acid,3-(6,7-dihydroxy-5-benzofuranyl)-,δ-lactone;8-Hydroxypsoralen;NSC 401269;Xanthotol
Categories:
Pharmaceutical Intermediates > Heterocyclic Compound

Description

Xanthotoxol is a biologically active linear furocoumarin, shows strong pharmacological activities as anti-inflammatory, antioxidant, 5-HT antagonistic, and neuroprotective effects.

Solid

Xanthotoxol is an 8-hydroxyfurocoumarin.

Xanthotoxol Basic Attributes

Molecular Weight：

202.16

Exact Mass：

202.16

EC Number：

217-923-1

NSC Number：

401269

DSSTox ID：

DTXSID50173910

HScode：

2932999099

Characteristics

PSA：

59.7

XLogP3：

0.72

Appearance：

Solid

Density：

1.5±0.1 g/cm3

Melting Point：

145 °C

Boiling Point：

428.1±45.0 °C at 760 mmHg

Flash Point：

212.7±28.7 °C

Refractive Index：

1.711

Water Solubility：

7279 mg/L @ 25 °C (est)

Vapor Pressure：

6.22E-08mmHg at 25°C

Safety Information

Transport codes：

2810

hazard class code：

safety instructions：

20-45-24/25

Precautionary statement(s)：

P264, P270, P301+P312, P330, P501

Hazard Statements：

H302

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 2 companies from 1 notifications to the ECHA C&L Inventory.

Drug Information

MeSH Entry Terms：

8-hydroxypsoralen

Xanthotoxol Use and Manufacturing

A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities.

Computed Properties

Molecular Weight:202.16
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Exact Mass:202.02660867
Monoisotopic Mass:202.02660867
Topological Polar Surface Area:59.7
Heavy Atom Count:15
Complexity:312
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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XANTHOTOXOL 99% Green powder Professional Producer Greenbo

CAS No.: 2009-24-7

Grade: Pharmaceutical Grade

Content: 99%

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