N-(1,1-Dimethylethyl)formamide
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N-(1,1-Dimethylethyl)formamide
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CAS No:
2425-74-3
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Formula:
C5H11NO
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Chemical Name:
N-(1,1-Dimethylethyl)formamide
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Synonyms:
Formamide,N-(1,1-dimethylethyl)-;Formamide,N-tert-butyl-;N-(1,1-Dimethylethyl)formamide;N-tert-Butylformamide;tert-Butylformamide;NSC 7082;N-Formyl-tert-butylamine;51597-77-4
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CAS No:
N-(1,1-Dimethylethyl)formamide Basic Attributes
101.15
101.15
1738869
219-369-6
GZ0P5X0IRF
7082
DTXSID2062408
Colorless liquid
2924199090
Characteristics
29.1
1.55770
0.903 g/mL at 25 °C(lit.)
16 °C
202 °C
203 °F
n20/D 1.433(lit.)
Sol in water and common hydrocarbon solvents.
0.27 mm Hg @ 25 deg C
Intravenous-Mouse LD50: 180 mg/kg
Thermal decomposition to emit toxic nitrogen oxide fumes
High boiling liquid
Safety Information
3
23-24/25
LQ1450000
Warehouse ventilated, low temperature and dry
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
An equimolar mixture with N-tert-butyl formamide underwent a sudden exotherm after placing in a bath at 60 °C and the tube contents were ejected vigorously as a small cloud.
N-(1,1-Dimethylethyl)formamide Use and Manufacturing
Isobutylene first reacts with sulfuric acid and then hydrogen cyanide to yield tert-butylformamide.
/Used/ as a solvent and in petroleum additives|Used as an intermediate in the manufacture of lubricating oil additives and miscellaneous chemicals.
Formamide, N-(1,1-dimethylethyl)-: INACTIVE
A HPLC method with UV detection was used for the determination of low mol wt amides in pharmaceutical matrixes. The method was based on Zorbax C8 or Alltech C18 column, mobile phase consisting of 3-5% MeCN in 0.1M phosphate buffer, & flow rate of 1-1.5 ml/min at the room temperature. By strongly retaining the sample matrix & allowing the amide analyte to elute, the method can be generally applied to many types of org matrix for pharmaceutical & agricultural products. /Amides/
Computed Properties
Molecular Weight:101.15
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:101.084063974
Monoisotopic Mass:101.084063974
Topological Polar Surface Area:29.1
Heavy Atom Count:7
Complexity:63
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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