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Home > Encyclopedia > N-(1,1-Dimethylethyl)formamide

N-(1,1-Dimethylethyl)formamide

N-(1,1-Dimethylethyl)formamide structure

N-(1,1-Dimethylethyl)formamide 

structure
  • CAS No:

    2425-74-3

  • Formula:

    C5H11NO

  • Chemical Name:

    N-(1,1-Dimethylethyl)formamide

  • Synonyms:

    Formamide,N-(1,1-dimethylethyl)-;Formamide,N-tert-butyl-;N-(1,1-Dimethylethyl)formamide;N-tert-Butylformamide;tert-Butylformamide;NSC 7082;N-Formyl-tert-butylamine;51597-77-4

  • Categories:

    Organic Chemistry  >  Amides

N-(1,1-Dimethylethyl)formamide Basic Attributes

101.15

101.15

1738869

219-369-6

GZ0P5X0IRF

7082

DTXSID2062408

Colorless liquid

2924199090

Characteristics

29.1

1.55770

0.903 g/mL at 25 °C(lit.)

16 °C

202 °C

203 °F

n20/D 1.433(lit.)

Sol in water and common hydrocarbon solvents.

0.27 mm Hg @ 25 deg C

Intravenous-Mouse LD50: 180 mg/kg

Thermal decomposition to emit toxic nitrogen oxide fumes

High boiling liquid

Safety Information

3

23-24/25

LQ1450000

Warehouse ventilated, low temperature and dry

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

An equimolar mixture with N-tert-butyl formamide underwent a sudden exotherm after placing in a bath at 60 °C and the tube contents were ejected vigorously as a small cloud.

Toxicity

moderately toxic

LD50 Mouse iv 180 mg/kg

N-(1,1-Dimethylethyl)formamide Use and Manufacturing

Methods of Manufacturing

Isobutylene first reacts with sulfuric acid and then hydrogen cyanide to yield tert-butylformamide.

Uses

/Used/ as a solvent and in petroleum additives|Used as an intermediate in the manufacture of lubricating oil additives and miscellaneous chemicals.

Formamide, N-(1,1-dimethylethyl)-: INACTIVE

A HPLC method with UV detection was used for the determination of low mol wt amides in pharmaceutical matrixes. The method was based on Zorbax C8 or Alltech C18 column, mobile phase consisting of 3-5% MeCN in 0.1M phosphate buffer, & flow rate of 1-1.5 ml/min at the room temperature. By strongly retaining the sample matrix & allowing the amide analyte to elute, the method can be generally applied to many types of org matrix for pharmaceutical & agricultural products. /Amides/

Computed Properties

Molecular Weight:101.15
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:101.084063974
Monoisotopic Mass:101.084063974
Topological Polar Surface Area:29.1
Heavy Atom Count:7
Complexity:63
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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