Methylprednisolone sodium succinate
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Methylprednisolone sodium succinate
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CAS No:
2375-03-3
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Formula:
C26H34O8.Na
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Chemical Name:
Methylprednisolone sodium succinate
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Synonyms:
Pregna-1,4-diene-3,20-dione,21-(3-carboxy-1-oxopropoxy)-11,17-dihydroxy-6-methyl-,monosodium salt,(6α,11β)-;Pregna-1,4-diene-3,20-dione,11β,17,21-trihydroxy-6α-methyl-,21-(hydrogen succinate),monosodium salt;Pregna-1,4-diene-3,20-dione,11β,17,21-trihydroxy-6α-methyl-,21-(hydrogen succinate),sodium salt;Succinic acid,21-monoester with 11β,17,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione,monosodium salt;6α-Methylprednisolone 21-sodium hemisuccinate;Solu-Medrol;Methylprednisolone sodium succinate;6α-Methylprednisolone 21-sodium succinate;U 9088;6α-Methylprednisolone sodium hemisuccinate;6α-Methylpregnisolone 21-sodium succinate;6α-Methylprednisolone sodium succinate;Solu-Medrone;Methylprednisolone hemisuccinate sodium;Sodium methylprednisolone succinate;Methylprednisolone succinate sodium;6-Methylprednisolone sodium succinate;Urbason Solubile;Metypred;NSC 48989
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CAS No:
Description
6α-Methylprednisolone 21-hemisuccinate sodium salt is a glucocorticoid of slightly longer half-life than that of Prednisolone. It has potential uses in antiinflammatory agents.
Characteristics
141.03000
0.88460
lyophilized powder
689.6ºC at 760mmHg
230.7ºC
LD50 oral in rat: > 5gm/kg
Safety Information
NONH for all modes of transport
3
61-40
53-22-36/37/39-45
TU4154060
T
P201-P281-P308 + P313
H351-H360
|Danger|H302 (27.12%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P264, P270, P280, P281, P301+P312, P302+P352, P308+P313, P312, P322, P330, P363, P405, and P501|Aggregated GHS information provided by 60 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Methylprednisolone sodium succinate Use and Manufacturing
6α-Methylprednisolone 21-Hemisuccinate is a glucocorticosteroid used in anti-inflammatory medication in the treatment of spinal cord injuries.
Computed Properties
Molecular Weight:497.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:497.21513732
Monoisotopic Mass:497.21513732
Topological Polar Surface Area:138
Heavy Atom Count:35
Complexity:981
Defined Atom Stereocenter Count:8
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes
Drug Function and Efficacy
Extract from the above information
Registered Holders
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LUPIN LTD
Active
United Kingdom
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白鳥製薬株式会社
Active
Japan
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Henan LIHUA Pharmaceutical Co., Ltd.
Active
China
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Methylprednisolone sodium succinate
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