Product
Supplier
Encyclopedia
Inquiry
Home > Encyclopedia > 2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid

2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid

2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid structure

2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid 

structure
  • CAS No:

    2387-71-5

  • Formula:

    C10H18N4O6

  • Chemical Name:

    2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid

  • Synonyms:

    Arginosuccinic acid;L-Argininosuccinic acid;L-Arginosuccinic acid;N-[[(S)-4-Amino-4-carboxybutyl]amino(imino)methyl]-L-aspartic acid;N-[[[(S)-4-Amino-4-carboxybutyl]amino](imino)methyl]-L-aspartic acid;(N(omega)-L-arginino)succinic acid;2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid;L-Aspartic acid, N-[[[(4S)-4-amino-4-carboxybutyl]amino]iminomethyl]-

Description

Solid


A likely impurity is fumaric acid. In neutral or alkaline solution it readily undergoes ring closure to the 'anhydride' (see below). Crystallise it from water by adding 1.5 volumes of EtOH. The barium salt is stable at 0-5o if dry. [Westfall Biochem J 77 135 1960, Ratner & Kunkemueller Biochemistry 5 1821 1966.]

2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid Basic Attributes

290.27

290.27

Characteristics

188

-4.7

1.2800 (rough estimate)

417.26°C (rough estimate)

1.6200 (estimate)

1.62(at 25℃)

2-[amino-(4-amino-4-carboxy-butyl)imino-methyl]aminobutanedioic acid Use and Manufacturing

Argininosuccinic acid participates in the fourth step of the urea cycle, with being cleaved to arginine and fumaric acid by argininosuccinic acid lyase (ASL). Argininosuccinic acid reduces reduced glutathione (GSH) level, and increases the production of reactive oxygen species in cerebral cortex and striatum. Argininosuccinic acid causes lipid peroxidation and protein oxidation, and induces oxidative stress in the developing rat brain[1][2].

Scan the QR Code to Share

Feedback & Suggestions
Send Message

Thank you for your feedback. If you require further assistance, please contact us by email at info@echemi.com or call us at +86-532-55729510.