Acid Blue 9

792.85

782.211365

223-339-8

86R7G3C26F

1602

DTXSID4034310

Reddish-violet powder or granules with a metallic lustre /sodium salt/

202.99000

9.02170

DryPowder

1.1666 (rough estimate)

283 °C (dec.)(lit.)

Soluble in water (5% at 20 deg C and 98 deg C) and in ethanol

LDLo intravenous in human: 33ug/kg

1602

3

BQ4725000

STABILITY OF LIQ FORMULATIONS CONTAINING BRILLIANT BLUE FCF (7-11.5 MO PERIOD) DECR AT AMBIENT TEMP; MOST IMPORTANT FACTOR DIFFUSE LIGHT

P261, P272, P280, P302+P352, P321, P333+P313, P363, P501

H317

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

All batches of this color additive when used as a drug shall meet the specifications, uses and restrictions, and labeling regulations contained in 21 CFR Part 74 and be certified in accordance with regulations in 21 CFR Part 80.|All batches of this color additive when used as a cosmetic shall meet the specifications, uses and restrictions, and labeling regulations contained in 21 CFR Part 74 and be certified in accordance with regulations in 21 CFR Part 80.|A batch of this straight color may be certified, in accordance with 21 CFR Part 82, for use in drugs and cosmetics, if such batch conforms to the requirements of 21 CFR 82.5 and to the specifications in 21 CFR Part 82.

Duggan M, Appleton H; Chemical Hazard Information Profile Draft Report. Brilliant Blue FCF, CAS No. 2650-18-2; Office of Toxic Substances USEPA Washington DC 19 pages (1981). Available data on the hazards of brilliant-blue-FCF, the disodium salt or the diammonium salt, is reviewed and a preliminary risk assessment is provided.|KHERA KS, MUNRO IC; A REVIEW OF THE SPECIFICATIONS AND TOXICITY OF SYNTHETIC FOOD COLORS PERMITTED IN CANADA; CRIT REV TOXICOL 6(2) 81 (1979). SPECIFICATIONS AND TOXICITY OF SYNTHETIC FOOD COLORS USED IN CANADA ARE DISCUSSED.

Not Classified

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)

FOLLOWING ADMIN OF A SINGLE ORAL DOSE OF BRILLIANT BLUE FCF AT EITHER 30 MUG/KG OR 3 MG/KG TO MALE OR FEMALE RATS, SUBSTANTIALLY ALL OF THE DOSE WAS EXCRETED UNCHANGED IN FECES WITHIN 72 HR. PRETREATING MALE RATS WITH UNLABELED BRILLIANT BLUE FCF IN THE DIET (30 MG/KG/DAY) FOR 21 DAYS PRIOR TO DOSING WITH (14)C-LABELED COLORING HAD NO EFFECT ON ROUTE OF EXCRETION OR THE TIME TAKEN TO ELIMINATE ALL OF THE LABEL. SIMILARLY, MALE MICE & GUINEA PIGS EXCRETED IN THE FECES ALL OF A SINGLE ORAL DOSE OF BRILLIANT FCF. THE LACK OF ABSORPTION & METABOLISM OF THE LABELED DYE IN GI TRACT OF ALL 3 SPECIES INVESTIGATED WAS CONFIRMED BY STUDIES USING ISOLATED LOOPS OF SMALL INTESTINE. NO RADIOACTIVITY WAS TAKEN UP BY THE FETUSES OF PREGNANT RATS GIVEN (14)C-LABELED BRILLIANT BLUE FCF.

For drug and cosmetic grades: volatile matter (at 135 °C), 10.0% max; ammonium chlorides and sulfates, 5.0% max; water-insoluble matter, 1.0% max; mixed oxides, 1.0% max; and ether extracts, 0.5% max

acid blue 9

Present at 0.001 wt% in a typical shampoo colorant /from table/

Textiles, apparel, and leather manufacturing|Benzenemethanaminium, N-ethyl-N-[4-[[4-[ethyl[(3-sulfophenyl)methyl]amino]phenyl](2-sulfophenyl)methylene]-2,5-cyclohexadien-1-ylidene]-3-sulfo-, inner salt, ammonium salt (1:2): ACTIVE|Approved by FDA for use in food, drugs and cosmetics, excluding use in eye area

PRODUCT ANALYSIS: /IN COLORS/ TITRATION WITH STANDARD TITANOUS CHLORIDE SOLUTION.|PRODUCT ANALYSIS: /IN COLORS/ SPECTROPHOTOMETRIC MEASUREMENTS.|DETECTION OF FOOD DYES WAS BY ION PAIR HIGH-PERFORMANCE CHROMATOGRAPHY.|ORGANIC DYES WERE DETERMINED BY TLC USING A METHYLCELLULOSE STATIONARY PHASE ON A PLASTIC SUPPORT & MOBILE PHASE OF 2.5% SODIUM ACETATE OR 2% SODIUM CITRATE, BOTH IN 5% AMMONIA.|For more Analytic Laboratory Methods (Complete) data for C.I. ACID BLUE 9 (6 total), please visit the HSDB record page.

Cosmetics -> Cosmetic colorant; Hair dyeing