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Estradiol, dipropionate

Estradiol, dipropionate structure

CAS No:
113-38-2
Formula:
C24H32O4
Chemical Name:
Estradiol, dipropionate
Synonyms:
Estra-1,3,5(10)-triene-3,17-diol (17β)-,3,17-dipropanoate;Estradiol,dipropionate;Estra-1,3,5(10)-triene-3,17-diol (17β)-,dipropanoate;Agofollin;Dimenformon dipropionate;Diovocylin;17β-Estradiol dipropionate;β-Estradiol dipropionate;3,17β-Estradiol dipropionate;Oestradiol 3,17-dipropionate;Ovocyclin dipropionate;Progynon DP;Nacyclyl;Diovocyclin;Diprostron;Ovocyclin P;Endofollicolina D. P.;Estroici;Estronex;Follicyclin P;Estradiol 3,17-dipropionate;Estradiol propionate;1,3,5(10)-Estratriene-3,17β-diol dipropionate;17β-Estradiol 3,17-dipropionate;3,17β-Dipropionoxyestra-1,3,5(10)-triene;Ovahormon Depot;Akrofolline
Categories:
Analytical Chemistry > Standard

Description

Estradiol dipropionate is a steroid ester.|Estradiol Dipropionate is the synthetic dipropionate ester of estradiol, a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. As the primary, most potent estrogen hormone produced by the ovaries, estradiol binds to and activates specific nuclear receptors. This agent exhibits mild anabolic and metabolic properties, and increases blood coagulability. (NCI04)

Estradiol, dipropionate Basic Attributes

Molecular Weight：

384.51

Exact Mass：

384.51

EC Number：

204-026-5

UNII：

NIG5418BXB

DSSTox ID：

DTXSID8023000

NCI Thesaurus Code：

C29770

Characteristics

PSA：

52.60000

XLogP3：

5.17990

Density：

1.14g/cm3

Melting Point：

104-105 °C

Boiling Point：

487.8ºC at 760mmHg

Flash Point：

238.5ºC

Refractive Index：

1.577

Water Solubility：

H2O: Insuluble (9.6E-5 g/L) (25 ºC)

Safety Information

hazard class code：

40-48

safety instructions：

22-24/25

RTECS Number：

KG4725000

Marks：

Precautionary statement(s)：

P201, P202, P260, P261, P263, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P330, P363, P405, P501

Hazard Statements：

H302

GHS Classification：

|Danger|H302 (20.25%): Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P263, P264, P270, P271, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P322, P330, P363, P405, and P501|Aggregated GHS information provided by 79 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH Entry Terms：

estradiol dipropionate

Estradiol, dipropionate Use and Manufacturing

Uses

estrogen

Use Classification：

Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C18 steroids (estrogens) and derivatives [ST0201]

Computed Properties

Molecular Weight:384.5
XLogP3:4.3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:384.23005950
Monoisotopic Mass:384.23005950
Topological Polar Surface Area:52.6
Heavy Atom Count:28
Complexity:601
Defined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes