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DL-Serine

DL-Serine structure

CAS No:
302-84-1
Formula:
C3H7NO3
Chemical Name:
DL-Serine
Synonyms:
Serine;Serine,DL-;DL-Serine;(±)-Serine;DL-Ser;NSC 9960;2-Azaniumyl-3-hydroxypropanoate
Categories:
Cosmetic Ingredient > Antistatic

Description

DL-Serine is a mixture of D-Serine and L-Serine.

Serine is an alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. It has a role as a fundamental metabolite. It is an alpha-amino acid and a polar amino acid. It contains a hydroxymethyl group. It is a conjugate base of a serinium. It is a conjugate acid of a serinate. It is a tautomer of a serine zwitterion.

DL-Serine Basic Attributes

Molecular Weight：

105.09

Exact Mass：

105.09

BRN：

1721402

EC Number：

206-130-6

NSC Number：

620355|118365|77689|9960

HScode：

29225000

Characteristics

PSA：

83.6

XLogP3：

-3.1

Appearance：

White Crystalline Powder

Density：

1.6 g/cu cm @ 22 deg C

Melting Point：

246 °C (decomp)

Boiling Point：

394.8ºC at 760 mmHg

Flash Point：

192.6±25.1 °C

Refractive Index：

1.519

Water Solubility：

H2O: 50.23 g/L (25 ºC)

Storage Conditions：

Store at RT.

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

36/37/38

safety instructions：

24/25-36-26

RTECS Number：

VT8100000

Marks：

Drug Information

MeSH Entry Terms：

poly-L-serine

DL-Serine Use and Manufacturing

Methods of Manufacturing

In the presence of excess copper carbonate, formaldehyde and glycine are used as raw materials to reflux, and the product is obtained by filtration, acidification, column chromatography and crystallization after cooling.

Uses

Pharmaceutical intermediates or APIs.

Manufacturing Info：

Serine: ACTIVE

Use Classification：

Food additives -> Flavoring Agents|Fatty Acyls [FA] -> Fatty Acids and Conjugates [FA01] -> Amino fatty acids [FA0110]

Food Additive Classes：

Flavoring Agents

Computed Properties

Molecular Weight:105.09
XLogP3:-3.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:105.042593085
Monoisotopic Mass:105.042593085
Topological Polar Surface Area:83.6
Heavy Atom Count:7
Complexity:72.6
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

Formaldehyde

Glycine

Downstream Products

Oxalic acid

Formaldehyde

Glycine

Acetaldehyde

Ammonia

Drug Function and Efficacy

Amino acids are the basic units that make up human proteins and enzymes, and are involved in human metabolism and various physiological functions.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Compound Amino Acid Injection for Children (18AA-Ⅰ)
Ingredients	The product is a compound preparation, and its components are as follows: Each 1000ml contains: Isoleucine (C6H13NO2) 3.1g Lysine acetate (C6H14N2O2·C2H4O2) 7.9g Phenylalanine (C9H11NO2) 2.7g Tryptophan (C11H12N2O2) 1.4g Histidine (C6H9N3O2) 2.1g Proline (C5H9NO2) 5.6g Serine (C3H7NO3) 3.8g Glutamic acid (C5H9NO4) 7.1g N-acetyl-L-tyrosine (C11H13NO4) 0.6g Leucine (C6H13NO2) 7.0g Methionine (C15H11NO2S) 1.3g Threonine
Indication	Not yet clear.
Specifications	250 ml: 16.85 g (total amino acids)
Manufacturer	Cisen Pharmaceutical Co., Ltd.

Compound Amino Acid Oral Solution (14AA)
Ingredients	This product is a compound preparation, and its components are as follows: each bottle contains 0.688g leucine, 0.563g isoleucine, 0.525g valine, 0.563g glycine, 0.500g proline, 0.481g alanine, 0.476g lysine (HCl), 0.375g arginine (base), 0.313g serine, 0.281g threonine, 0.150g histidine (base), 0.063g methionine, 0.063g phenylalanine, and 0.041g tryptophan.
Indication	Not yet clear.
Specifications	Each bottle is 50 ml (containing 5.082 grams of amino acids in total)
Manufacturer	Hubei Provincial Bafeng Pharmaceuticals & CHEMICALS SHARE Co., Ltd.

Compound Amino Acid Injection for Children (18AA-Ⅰ)
Ingredients	The product is a compound preparation, and its components are as follows: Each 1000ml contains: Isoleucine (C6H13NO2) 3.1g Lysine acetate (C6H14N2O2·C2H4O2) 7.9g Phenylalanine (C9H11NO2) 2.7g Tryptophan (C11H12N2O2) 1.4g Histidine (C6H9N3O2) 2.1g Proline (C5H9NO2) 5.6g Serine (C3H7NO3) 3.8g Glutamic acid (C5H9NO4) 7.1g N-acetyl-L-tyrosine (C11H13NO4) 0.6g Leucine (C6H13NO2) 7.0g Methionine (C15H11NO2S) 1.3g Threonine
Indication	Not yet clear.
Specifications	250ml:16.85g (total amino acids)
Manufacturer	Anhui Double-Crane Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Yuanda Bafeng (Hubei) Pharmaceutical Co., Ltd.

China
Active
Shanghai Primano Amino Acid Co., Ltd.

China
Active
Jinyao Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

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