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Sinomenine

Sinomenine structure

CAS No:
115-53-7
Formula:
C19H23NO4
Chemical Name:
Sinomenine
Synonyms:
Morphinan-6-one,7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-,(9α,13α,14α)-;Sinomenine;9α,13α,14α-Morphinan-6-one,7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-;(9α,13α,14α)-7,8-Didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one;Cucoline;Kukoline;Sinomenin;1089764-83-9
Categories:
Biochemical Engineering > Biosynthetic Natural Products

Description

Sinomenine, an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation[1]. Sinomenine also is an activator of μ-opioid receptor[2].

Sinomenine Basic Attributes

Molecular Weight：

329.39

Exact Mass：

329.39

EC Number：

204-094-6

HScode：

29399990

Characteristics

PSA：

XLogP3：

1.25

Appearance：

White powder

Density：

1.2012 (rough estimate)

Melting Point：

162 °C

Boiling Point：

466.98°C (rough estimate)

Flash Point：

264.4±30.1 °C

Refractive Index：

1.5000 (estimate)

Storage Conditions：

Store at +4°C

Vapor Pressure：

0mmHg at 25°C

Toxicity：

LD50 orally in mice: 580 mg/kg (Fu)

Specific rotation：

D26 -71° (c = 2.1 in alc)

Safety Information

Packing level：

III

Hazard category：

6.1(b)

Transport codes：

1544

wgk germany：

hazard class code：

45-46-23/24/25-36/37/38-20/21/22-48/20/22-40-22-63

safety instructions：

53-22-26-36/37/39-45-36/37-24/25

RTECS Number：

QD2170000

Marks：

T,Xn

Precautionary statement(s)：

P301 + P312 + P330-P305 + P351 + P338

Hazard Statements：

H302-H315-H319-H335

Sinomenine Use and Manufacturing

weak abortifacient, immunosuppressant, analgesic, antiinflammatory; LD50 (po) 580 mg/kg; (ip) 285 mg/kg(mouse)

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Sinomenine CAS 115-53-7 for Scientific Research Chemical Reagents Use only

CAS No.: 115-53-7

Grade: Pharmaceutical Grade

Content: 99%

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Guide of Sinomenine

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Recommended Suppliers
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Sinomenine

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