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Nicotinic acid mononucleotide

Nicotinic acid mononucleotide structure

Nicotinic acid mononucleotide 

structure
  • CAS No:

    321-02-8

  • Formula:

    C11H14NO9P

  • Chemical Name:

    Nicotinic acid mononucleotide

  • Synonyms:

    Pyridinium,3-carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)-,inner salt;Pyridinium,3-carboxy-1-β-D-ribofuranosyl-,hydroxide,5′-(dihydrogen phosphate),inner salt;3-Carboxy-1-β-D-ribofuranosylpyridinium hydroxide,5′-phosphate,inner salt;Nicotinic acid mononucleotide;Nicotinic acid ribonucleotide;Nicotinate mononucleotide;Nicotinic acid ribotide;3-Pyridinecarboxylic acid,mononucleotide;Deamido-NMN;β-Nicotinic acid mononucleotide;Nicotinic mononucleotide;Deamido nicotinamide ribonucleotide;Nicotinate ribonucleotide;7413-38-9;14922-97-5;94628-21-4;909881-30-7;1083058-34-7;1262326-83-9;1262326-86-2

  • Categories:

    Biochemical Engineering  >  Saccharides

Description

Nicotinic acid mononucleotide (NAMN) is formed from nicotinic acid (NA) via the nicotinic acid phosphoribosyltransferase in the biosynthesis of NAD+. Nicotinate mononucleotide is a substrate for nicotinamide mononucleotide/Nicotinic acid mononucleotide adenylyltransferase[1][2].

Nicotinic acid mononucleotide Basic Attributes

336.21200

336.04800

Characteristics

167.44000

-1.59920

-20ºC

Safety Information

NONH for all modes of transport

3

Drug Information

nicotinate mononucleotide

Nicotinic acid mononucleotide Use and Manufacturing

A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH.

Computed Properties

Molecular Weight:335.20
XLogP3:-2.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:335.04061802
Monoisotopic Mass:335.04061802
Topological Polar Surface Area:161
Heavy Atom Count:22
Complexity:449
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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