Chlorogenic acid
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Chlorogenic acid
structure -
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CAS No:
327-97-9
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Formula:
C16H18O9
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Chemical Name:
Chlorogenic acid
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Synonyms:
Cyclohexanecarboxylic acid,3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxy-,(1S,3R,4R,5R)-;Chlorogenic acid;Cyclohexanecarboxylic acid,3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-,[1S-(1α,3β,4α,5α)]-;Cyclohexanecarboxylic acid,3-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1,4,5-trihydroxy-,(1S,3R,4R,5R)-;(1S,3R,4R,5R)-3-[[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-1,4,5-trihydroxycyclohexanecarboxylic acid;3-Caffeoylquinic acid;3-O-Caffeoylquinic acid;3-(3,4-Dihydroxycinnamoyl)quinic acid;Caffeoylquinic acid;3-O-(3,4-Dihydroxycinnamoyl)-D-quinic acid;NSC 407296;Heriguard;NSC 70861;SW 85834;5-Chlorogenic acid;108657-60-9;12626-41-4;15076-00-3;16310-14-8;16431-26-8;16431-25-7
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CAS No:
Description
Chlorogenic acid is a major phenolic compound in coffee and tea. It plays several important and therapeutic roles such as antioxidant activity, antibacterial, hepatoprotective, cardioprotective, anti-inflammatory, antipyretic, neuroprotective, anti-obesity, antiviral, anti-microbial, anti-hypertension.
Characteristics
164.75000
-0.4
Solid
1.65g/cm3
206-207 °C
665ºC at 760mmHg
245.5ºC
-37 ° (C=1, H2O)
soluble in hot water;40 mg/mL at 25 °C
0-6ºC
LDLo intraperitoneal in rat: 4gm/kg
Safety Information
NONH for all modes of transport
3
R68
S24/25
GU8480000
Xi
Stable under normal temperatures and pressures.
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P280, P301+P312, P302+P352, P303+P361+P353, P304+P312, P304+P340, P305+P351+P338, P312, P322, P330, P337+P313, P363, P370+P378, P403+P235, P501
H225
Chlorogenic acid Use and Manufacturing
An antioxidant, also slows the release of glucose into the bloodstream after a meal.Chlorogenic Acid is an analog of caffeic acid that displays antioxidant, analgesic, antipyretic and chemopreventive activity. Chlorogenic acid inhibits Bcr-Abl(the fusion protein of Bcr and c-Abl) tyrosine kinase and triggers MAP kinases p38-dependent apoptosis.
Drug Function and Efficacy
broad-spectrum antibacterial and antiviral (inhibits influenza virus, adenovirus, etc.)
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