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Cuprizone

Cuprizone structure

CAS No:
370-81-0
Formula:
C14H22N4O2
Chemical Name:
Cuprizone
Synonyms:
Ethanedioic acid,1,2-bis(2-cyclohexylidenehydrazide);Oxalic acid,bis(cyclohexylidenehydrazide);Ethanedioic acid,bis(cyclohexylidenehydrazide);Cuprizone;Biscyclohexanone oxalyldihydrazone;Oxalic bis(cyclohexylidene)hydrazide;NSC 4283;Bis(1,5-cyclohexanone) oxal dihydrazone;Chromium(III) ionophore III
Categories:
Chemical Reagents > Organic Reagents

Description

white powder

Cuprizon is an organooxygen compound and an organonitrogen compound. It derives from an alpha-amino acid.|Copper chelator that inhibits monoamine oxidase and causes liver and brain damage.

Cuprizone Basic Attributes

Molecular Weight：

278.35

Exact Mass：

278.35

BRN：

2388004

EC Number：

206-729-2

UNII：

5N16U7E0AO

NSC Number：

4283

HScode：

29280090

Characteristics

PSA：

82.9

XLogP3：

0.85

Appearance：

White Powder

Density：

1.3±0.1 g/cm3

Melting Point：

210-214 °C(lit.)

Refractive Index：

1.626

Water Solubility：

soluble in alcohol. Insoluble in water.

Storage Conditions：

2-8°C

Safety Information

Packing level：

I; II; III

Hazard category：

6.1

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

21/22

safety instructions：

24/25-2

RTECS Number：

RO2520000

Marks：

Precautionary statement(s)：

P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, P501

Hazard Statements：

H302

Drug Information

MeSH：

A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)|Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

MeSH Entry Terms：

Biscyclohexanone Oxaldihydrazone

Cuprizone Use and Manufacturing

Uses

Photometric determination of copper (II); experimental study of mitochondrial metabolism

Manufacturing Info：

Ethanedioic acid, 1,2-bis(2-cyclohexylidenehydrazide): ACTIVE

Computed Properties

Molecular Weight:278.35
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:278.17427596
Monoisotopic Mass:278.17427596
Topological Polar Surface Area:82.9
Heavy Atom Count:20
Complexity:373
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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