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Home > Encyclopedia > 3-FLUORO-4-METHOXYBENZYLBROMIDE

3-FLUORO-4-METHOXYBENZYLBROMIDE

3-FLUORO-4-METHOXYBENZYLBROMIDE structure

3-FLUORO-4-METHOXYBENZYLBROMIDE 

structure
  • CAS No:

    331-61-3

  • Formula:

    C8H8BrFO

  • Chemical Name:

    3-FLUORO-4-METHOXYBENZYLBROMIDE

  • Synonyms:

    3-FLUORO-4-METHOXYBENZYLBROMIDE;3-Fluoro-4-methoxybenzylbromide,98%;4-(broMoMethyl)-2-fluoro-1-Methoxybenzene;4-(Bromomethyl)-2-fluoroanisole,4-(Bromomethyl)-2-fluoro-1-methoxybenzene,4-(Bromomethyl)-2-fluorophenylmethylether

Description

White solid

3-FLUORO-4-METHOXYBENZYLBROMIDE Basic Attributes

219.05

217.974243

DTXSID10379097

2909309090

Characteristics

9.2

2.6

1.5±0.1 g/cm3

44-46°C

245.1°C at 760 mmHg

121.7±7.4 °C

1.532

Safety Information

III

8

UN3261

R36/37/38

S26-S36/37/39

C: Corrosive;

P260, P261, P264, P271, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P337+P313, P363, P403+P233, P405, P501

H314

|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P261, P264, P271, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P337+P313, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 8 companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

3-FLUORO-4-METHOXYBENZYLBROMIDE Use and Manufacturing

To a solution of 64 (2.35 g, 15.05 mmol) and triethylamine (3.15 mL, 22.58 mmol) in DCM (50 mL, anhydrous) at r.t. was added mesyl chloride (1.41 mL, 18.06 mmol) dropwise. After 15 min, the reaction was diluted with DCM (50 mL) and the organic layer washed with sat. aq. NaHC0

Computed Properties

Molecular Weight:219.05
XLogP3:2.6
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:217.97426
Monoisotopic Mass:217.97426
Topological Polar Surface Area:9.2
Heavy Atom Count:11
Complexity:121
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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