Rosmarinic acid
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Rosmarinic acid
structure -
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CAS No:
20283-92-5
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Formula:
C18H16O8
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Chemical Name:
Rosmarinic acid
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Synonyms:
Benzenepropanoic acid,α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxy-,(αR)-;Cinnamic acid,3,4-dihydroxy-,2-ester with 3-(3,4-dihydroxyphenyl)lactic acid;Benzenepropanoic acid,α-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-,[R-(E)]-;Rosmarinic acid;Benzenepropanoic acid,α-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-3,4-dihydroxy-,(αR)-;(αR)-α-[[(2E)-3-(3,4-Dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4-dihydroxybenzenepropanoic acid;Rosemary acid;Rosemaric acid;RM 21A;Mamorekku RUH 2;Meiji Red Perilla Polyphenol;trans-Rosmarinic acid;Labiatenic acid;Labiatic acid;NPLC 0542;SYL 001
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CAS No:
Description
Rosmarinic acid (RA) is a widespread phenolic ester compound in the plants. Rosmarinic acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 μM, respectively.
Characteristics
144.52000
2.4
Solid
1.547g/cm3
169-171.5 °C
694.7ºC at 760 mmHg
254.5ºC
1.713
soluble in ethanol, DMSO or dimethyl formamide to approximately 25 mg/mL
2.92E-20mmHg at 25°C
Safety Information
NONH for all modes of transport
3
R36/38
S26; S37/39
GD8990000
Xi
P273-P301 + P310
H301-H400
Rosmarinic acid Use and Manufacturing
1. Rosmarinic Acid is a phenolic compound with antioxidant and anti-inflammatory activity. Rosmarinic Acid has been shown to inhibit againts peroxidative damage to biomembranes. Rosmarinic Acid also suppresses endotoxin-induced activation of complement and concomitant prostacyclin biosynthesis.
2. An activator of GPR35.
Drug Function and Efficacy
Antioxidant, anti-inflammatory, and potential neuroprotective properties
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