2,5-Piperazinedione
-
2,5-Piperazinedione
structure -
-
CAS No:
106-57-0
-
Formula:
C4H6N2O2
-
Chemical Name:
2,5-Piperazinedione
-
Synonyms:
2,5-Piperazinedione;Cycloglycylglycine;α,γ-Diacipiperazine;Diglycolyl diamide;2,5-Diketopiperazine;2,5-Dioxopiperazine;Glycylglycine lactam;Glycine,N-glycyl-,cyclic peptide;Cyclo(glycylglycyl);Cyclodiglycine;Diketopiperazine;Cyclo(Gly-Gly);Glycine,bimol. cyclic peptide;NSC 26345;Glycine cyclic dimer
- Categories:
-
CAS No:
Description
Piperazine-2,5-dione is a cyclic peptide that is piperazine in which the hydrogens at positions 2 and 5 are replaced by oxo groups. It is a member of 2,5-diketopiperazines and a cyclic peptide.
2,5-Piperazinedione Basic Attributes
114.1
114.10
112112
203-411-5
240L69DTV7
26345
DTXSID8059342
2933599090
Characteristics
58.2
-2.93
White to slightly yellow Crystalline Powder
1.2±0.1g/cm3
312 °C (decomp)
573.7±43.0°C at 760 mmHg
301.9±28.3°C
1.649
soluble in water (142mg/L).
Store below +30°C.
Safety Information
NONH for all modes of transport
3
24/25
TL6325250
P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, P501
H315
|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 2 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
2,5-Piperazinedione Use and Manufacturing
Derived from the condensation of glycine. Mix glycine and ethylenediamine at a ratio of 1:5, then stir and heat, react at 174-176°C for 50 min, then place in an ice room, filter out the crystals, wash with methanol, and dry to obtain glycinyl anhydride. It can also be prepared by condensation of glycine in dehydrated glycerol.
Used as a biochemical reagent. Glycylglycine can be obtained by hydrolysis with alkali, acid or hot water.
2,5-Piperazinedione: ACTIVE
Computed Properties
Molecular Weight:114.10
XLogP3:-1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Exact Mass:114.042927438
Monoisotopic Mass:114.042927438
Topological Polar Surface Area:58.2
Heavy Atom Count:8
Complexity:116
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Recommended Suppliers of 2,5-Piperazinedione
-
![China]()
CN
8 YRS
Business licensed Certified factoryManufactory Supplier of Biochemicals Ingredients,Vitamin Amino Acid Ingredients,Cosmestic Ingredients,Pharma Chemicals,Organic Fine Chemicals,Food Nutrient Ingredients,Natural Plant Ingredients,APIS Intermidiates,Daily Chemicals,Agricultural Chemicals,Surfactant Chemicals,Ultraviolet Absorbents,Antioxidant Ingredients,Scientific Research Chemical,Flavors and Fragrances ChemicalsInquiryCAS No.: 106-57-0Grade: Pharmaceutical GradeContent: 99% -
![China]()
CN
5 YRS
Business licensedTrader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives
Learn More Other Chemicals
-
(9β,11β,16β)-21-(Acetyloxy)-9,11-epoxy-17-hydroxy-16-methylpregna-1,4-diene-3,20-dione
912-38-9
-
(S)-4-Thiazolidinecarboxylic acid
45521-09-3
-
DL-CYSTINEHYDROCHLORIDE
90350-38-2
-
Peptones, beef Formula
91079-38-8
-
Epidermal Growth Factor Formula
62253-63-8
-
γ-L-Glutamyl-selenomethyl-L-selenocysteine Formula
26046-89-9
-
BOC-D-ARG(TOS)-OH ETOAC Structure
114622-81-0
-
β-Aminobenzenebutanoic acid Structure
15099-85-1
-
What is AC-ARG-OH 2H2O
210545-23-6
-
What is Acetochlor OA
194992-44-4