 Home > Encyclopedia > Moroxydine hydrochloride

Moroxydine hydrochloride

Moroxydine hydrochloride structure

CAS No:
3160-91-6
Formula:
C6H13N5O.ClH
Chemical Name:
Moroxydine hydrochloride
Synonyms:
4-Morpholinecarboximidamide,N-(aminoiminomethyl)-,hydrochloride (1:1);4-Morpholinecarboxamidine,N-amidino-,monohydrochloride;4-Morpholinecarboximidamide,N-(aminoiminomethyl)-,monohydrochloride;Guanidine,4-morpholinecarboximidoyl-,hydrochloride;ABOB hydrochloride;Spenitol;Flumidin;Virustat;N1,N1-Anhydrobis(β-hydroxyethyl)biguanide hydrochloride;4-(Amidinoamidino)morpholine hydrochloride;Morpholinobiguanide monohydrochloride;Morpholinobiguanide hydrochloride;Virusmin;Moroxydine hydrochloride;Malinguchlorate;Miejunging;8058-46-6;1195550-67-4
Categories:
Active Pharmaceutical Ingredients > Synthetic Anti-infective Drugs

Request for Quotation

Moroxydine hydrochloride Basic Attributes

Molecular Weight：

207.66

Exact Mass：

207.089

EC Number：

221-612-6

HScode：

2934999090

Characteristics

PSA：

101

XLogP3：

0.76700

Appearance：

white crystalline powder

Melting Point：

211-212 °C

Boiling Point：

327°C at 760 mmHg

Flash Point：

151.6ºC

Water Solubility：

>31.1 [ug/mL]

Safety Information

wgk germany：

hazard class code：

36/37/38

safety instructions：

26-37/39

RTECS Number：

QD9815000

Marks：

Precautionary statement(s)：

P264, P280, P302+P352, P305+P351+P338, P321, P332+P313, P337+P313, P362

Hazard Statements：

H315

Moroxydine hydrochloride Use and Manufacturing

Methods of Manufacturing

(1) to the 10L in the reactor with mechanical stirrer are sequentially added diethylene glycol 2.1 kg, dicy 2.0 kg, ammonium chloride 1.4 kg, quality quality concentration is 30percent sulfuric acid aqueous solution of 0.5 kg, the seal under stirring, every minutes to 3 degrees centigrade to the temperature increase speed of 120 °C, reactor pressure to rise to 0.3 MPa, reaction 1 hour later, natural cooling the reaction temperature to the room temperature, to obtain white milk;(2) the white cream is transferred to the 50L in glass autoclave, add 95percent ethanol 15 kg, heating reflux reaction 30 minutes to get mixed solution, the mixed fluid after filter drum heat filter in the crystallization kettle, the filtrate is cooled to room temperature in the crystallization kettle, separating white crystal, after centrifugal separation, the 80 °C after hot blast oven drying and under the conditions can be obtained trunk guanidine morpholine hydrochloride 5.2 kg, to dicy the idea receives rate to 81percent.(3) The comparative experimental procedure (2) obtained in step morpholine hydrochloride was added to the 100L glass reactor, weighed 15Kg dicyandiamide was added to the reactor, the stirring reactor was heated to 140 , reactant in the molten state, the reaction was stirred for 3 hours, heating was stopped, cooled to room temperature.(4) The 40Kg95percent ethanol into a reactor, heated to reflux and stirred for 30 minutes, filtered hot and cooled to crystallize kettle crystallized white solid after centrifugation, oven dried by hot air to give a white morpholino amidine guanidine hydrochloride 17.0Kg ( morpholine total income was 48percent, in order to gauge their dicyandiamide 46percent yield).

Uses

Moroxydine is an antiviral used against a number of RNA and DNA viruses.

Drug Function and Efficacy

This product can inhibit viral DNA and RNA polymerase, thereby inhibiting viral reproduction. On human embryonic kidney cells, 1% concentration has a significant inhibitory effect on DNA viruses (adenovirus, herpes virus) and RNA viruses (echovirus), and has an inhibitory effect on all stages of the viral proliferation cycle. It has no direct effect on free viral particles.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Morphoguanidine hydrochloride tablets
Ingredients	The main ingredient of this product is morpholinoguanidine hydrochloride.
Indication	Not yet clear.
Specifications	0.1g
Manufacturer	Guangdong Songxia Pharmaceutical Co., Ltd.

Morphoguanidine hydrochloride tablets
Ingredients	The main ingredient of this product is morpholine hydrochloride, and its chemical name is: N-N-(2-guanidino-ethylimino)-morpholine hydrochloride.
Indication	Not yet clear
Specifications	0.1g
Manufacturer	Gai Tianli Pharmaceutical Holding Group East China Pharmaceutical Co., Ltd.

Ganmaoqing Capsules
Ingredients	Andrographis paniculata leaves, Isatis indigotica leaves, Isatis indigotica root, Calendula officinalis, Rhizoma Atractylodis Macrocephalae, Sesamum indica, Paracetamol, Chlorpheniramine Maleate, Guanidine Hydrochloride, etc.
Indication	Drug interactions may occur if used with other drugs. Please consult your doctor or pharmacist for details.
Specifications	Each tablet contains 0.5g (containing 24mg of acetaminophen)
Manufacturer	Guangdong Eashu Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

Yili Pharmaceutical Co., Ltd.

China
Active
Hunan Qianjin Xiangjiang Pharmaceutical Co., Ltd.

China
Active
Hunan Jiudian HONGYANG Pharmaceutical Co., Ltd.

China
Active

See More Registered Holders

Recommended Suppliers of Moroxydine hydrochloride

Hangzhou Dawn Ray Pharmaceutical Co.,Ltd Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of D-Biotin,Tobramycin base,L(-)-Carnitine base,Polymyxin B sulfate USP,Kanamycin sulfate monohydrate,Finasteride 99% USP

Moroxydine hydrochloride China manufacture 98%min with DMF /GMP

CAS No.: 3160-91-6

Inquiry
Hangzhou KieRay Chem Co.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of fine chemicals,pharmaceutical materials

Moroxydine hydrochloride

CAS No.: 3160-91-6

Grade: industrial Grade

Content: 98%

Inquiry
Hubei KDG Web Science&Technology Co.,Ltd Contact Supplier

CN
2 YRS

Business licensed

Trader Supplier of Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin

Best Seller High Quality Moroxydine hydrochloride CAS 3160-91-6

CAS No.: 3160-91-6

Grade: Pharmaceutical Grade

Content: 99%

Inquiry