Fast Orange

338.27

338.27

222-429-4

E27LT0986O

15975

DTXSID6029258

Reddish shade of orange|Strong bright orange|Orange powder ... paste

2927000090

133

5.72 (est)

DryPowder; Liquid

1.52 g/cu cm (est)

298-300 °C

597.9±50.0 °C at 760 mmHg

315.4±30.1 °C

1.712

In water, 0.13 mg/L at 25 deg C (est)

9.32X10-12 mm Hg at 25 deg C (est)

Henry's Law constant = 9.1X10-15 atm-cu m/mole at 25 °C (est)

Molar volume = 222 cu cm (est)|Hydroxyl radical reaction rate constant = 1.75X10-11 cu cm/molec-sec at 25 °C (est)

92.33 kJ/mole (est)

1325

3

10-68-40-36

16-36/37-26

QL3854000

Xn,Xi

P281

H341-H351

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.

|Warning|H319 (87.89%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]|P264, P280, P305+P351+P338, and P337+P313|Aggregated GHS information provided by 891 companies from 8 notifications to the ECHA C&L Inventory.

C.I. Pigment Orange 5's production and use in paints(1) and printing inks(2) may result in its release to the environment through various waste streams(SRC).

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 1.3X10+5(SRC), determined from a structure estimation method(2), indicates that C.I. Pigment Orange 5 is expected to be immobile in soil(SRC). Volatilization of C.I. Pigment Orange 5 from moist soil surfaces is not expected to be an important fate process(SRC) given an estimated Henry's Law constant of 9.1X10-15 atm-cu m/mole(SRC), using a fragment constant estimation method(3). C.I. Pigment Orange 5 is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 9.3X10-12 mm Hg(SRC), determined from a fragment constant method(4). Biodegradation data were not available(SRC, 2009).|AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 1.3X10+5(SRC), determined from a structure estimation method(2), indicates that C.I. Pigment Orange 5 is expected to adsorb to suspended solids and sediment(SRC). Volatilization from water surfaces is not expected(3) based upon an estimated Henry's Law constant of 9.1X10-15 atm-cu m/mole(SRC), developed using a fragment constant estimation method(4). According to a classification scheme(5), an estimated BCF of 10(SRC), from an estimated log Kow of 5.7(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Biodegradation data were not available(SRC, 2009).|ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), C.I. Pigment Orange 5, which has an estimated vapor pressure of 9.3X10-12 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase C.I. Pigment Orange 5 may be removed from the air by wet or dry deposition(SRC). C.I. Pigment Orangee 5 contains functional groups that are typically chromophores which absorb at wavelengths >290 nm(3); therefore C.I. Pigment Orange 5 may be susceptible to direct photolysis by sunlight(SRC).

C.I. Pigment Orange 5 is not expected to undergo hydrolysis in the environment due to the lack of functional groups that hydrolyze under environmental conditions(1). C.I. Pigment Orange 5 contains functional groups which are typically chromophores and absorb at wavelengths >290 nm(1); therefore C.I. Pigment Orange 5 may be susceptible to direct photolysis by sunlight(SRC).

An estimated BCF of 10 was calculated for C.I. Pigment Orange 5(SRC), using an estimated log Kow of 5.7(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

Using a structure estimation method based on molecular connectivity indices(1), the Koc of C.I. Pigment Orange 5 can be estimated to be 1.3X10+5(SRC). According to a classification scheme(2), this estimated Koc value suggests that C.I. Pigment Orange 5 is expected to be immobile in soil.

The Henry's Law constant for C.I. Pigment Orange 5 is estimated as 9.1X10-15 atm-cu m/mole(SRC) using a fragment constant estimation method(1). This Henry's Law constant indicates that C.I. Pigment Orange 5 is expected to be essentially nonvolatile from water surfaces(2). The Henry's Law constant of C.I. Pigment Orange 5 indicates that volatilization from moist soil surfaces is not expected(SRC). C.I. Pigment Orange 5 is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 9.3X10-12 mm Hg(SRC), determined from a fragment constant method(3).

Occupational exposure to C.I. Pigment Orange 5 may occur through inhalation of dust and dermal contact with this compound at workplaces where C.I. Pigment Orange 5 is produced or used. Use data indicate that the general population may be exposed to C.I. Pigment Orange 5 via dermal contact with consumer products containing this compound. (SRC)

/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/|/SRP:/ Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in severe respiratory distress. Positive-pressure ventilation techniques with a bag valve mask device may be beneficial. Consider drug therapy for pulmonary edema ... . Consider administering a beta agonist such as albuterol for severe bronchospasm ... . Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start IV administration of D5W /SRP: "To keep open", minimal flow rate/. Use 0.9% saline (NS) or lactated Ringer's if signs of hypovolemia are present. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/

/HUMAN EXPOSURE STUDIES/ Eight patients suffering from pigmented contact dermatitis caused by the commercial Brilliant Lake Red R were patch tested with purified Sudan I and its several chemical analogs. Positive reactions were observed to Sudan I, Orange SS, Brilliant Lake Red R, Vacanceine Red, Yellow OB and Sudan II. Negative patch tests were obtained with Toluidine Red, Permanent Orange /Pigment Orange 5/, Lithol Red and Sudan III. The commercial Brilliant Lake Red R, which is said to be the most important causative agent of pigmented contact dermatitis, contained Sudan I as a major impurity. The patients reacting to Brilliant Lake Red R always gave a positive reaction to Sudan I, but those reacting to Sudan I did not always give a positive reaction to Brilliant Lake Red R. ...

1-((2,4-dinitrophenyl)azo)-2-naphthalenol

Custom compounding of purchased resin|2-Naphthalenol, 1-[2-(2,4-dinitrophenyl)diazenyl]-: ACTIVE|... relatively low hiding power and good lightfastness in full shades, but poor tint lightfastnesds. It shows poor bleed but acceptable base resistance