Palmatine
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Palmatine
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CAS No:
3486-67-7
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Formula:
C21H22NO4
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Chemical Name:
Palmatine
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Synonyms:
Dibenzo[a,g]quinolizinium,5,6-dihydro-2,3,9,10-tetramethoxy-;Berbinium,7,8,13,13a-tetradehydro-2,3,9,10-tetramethoxy-;Palmatine;5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium;Berbericinine;O,O-Dimethyldemethyleneberberine;Depiline;Fibrauretin;Huang Teng Su;Fibrauretine;2,3,9,10-Tetramethoxy-5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium;123363-46-2;11049-99-3;947323-43-5
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CAS No:
Description
Palmatine is an orally active and irreversible indoleamine 2,3-dioxygenase 1 (IDO-1) inhibitor. Palmatine can ameliorate DSS-induced colitis by mitigating colonic injury, preventing gut microbiota dysbiosis, and regulating tryptophan catabolism. Palmatine has the potential for colitis treatment[1].
Palmatine is a berberine alkaloid and an organic heterotetracyclic compound. It has a role as a plant metabolite.
Palmatine Use and Manufacturing
Emodin, palmatine, palmetate, tetrandrine, Berbericinine, Columbin, Fibrauretin, Calystigine
Computed Properties
Molecular Weight:352.4
XLogP3:3.7
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:352.15488318
Monoisotopic Mass:352.15488318
Topological Polar Surface Area:40.8
Heavy Atom Count:26
Formal Charge:1
Complexity:475
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It can quickly eliminate toxins from the body surface, have antibacterial effects, and promote the secretion of bile and pancreas.
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