Dioxindole
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Dioxindole
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CAS No:
61-71-2
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Formula:
C8H7NO2
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Chemical Name:
Dioxindole
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Synonyms:
2H-Indol-2-one,1,3-dihydro-3-hydroxy-;2-Indolinone,3-hydroxy-;Oxindole,3-hydroxy-;1,3-Dihydro-3-hydroxy-2H-indol-2-one;Dioxindole;3-Hydroxy-2-indolinone;NSC 26319;3-Hydroxyoxindole;2,3-Dihydro-3-hydroxy-2-oxo-1H-indole;3-Hydroxy-2,3-dihydro-1H-indol-2-one;3-Hydroxy-1,3-dihydroindol-2-one;71711-19-8
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CAS No:
Description
ChEBI: An oxindole that is 1,3-dihydro-2H-indol-2-one substituted by a hydroxy group at position 3.
3-hydroxyindolin-2-one is an oxindole that is 1,3-dihydro-2H-indol-2-one substituted by a hydroxy group at position 3. It is a member of oxindoles and a member of hydroxyindoles.
Safety Information
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Drug Information
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. Cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system. (See all compounds classified as Cholinesterase Inhibitors.)|A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414) (See all compounds classified as Monoamine Oxidase Inhibitors.)
3-hydroxy-2-oxoindole
Computed Properties
Molecular Weight:149.15
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Exact Mass:149.047678466
Monoisotopic Mass:149.047678466
Topological Polar Surface Area:49.3
Heavy Atom Count:11
Complexity:181
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes