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Home > Encyclopedia > 2-(Dimethylamino)ethanol

2-(Dimethylamino)ethanol

2-(Dimethylamino)ethanol structure

2-(Dimethylamino)ethanol 

structure
  • CAS No:

    108-01-0

  • Chemical Name:

    2-(Dimethylamino)ethanol

  • Synonyms:

    Ethanol,2-(dimethylamino)-;2-(Dimethylamino)ethanol;Deanol;(N,N-Dimethylamino)ethanol;β-Dimethylaminoethyl alcohol;N,N-Dimethylethanolamine;DMAE;β-Hydroxyethyldimethylamine;Bimanol;β-(Dimethylamino)ethanol;(Dimethylamino)ethanol;Dimethyl(2-hydroxyethyl)amine;Propamine A;N-(2-Hydroxyethyl)dimethylamine;2-(N,N-Dimethylamino)ethanol;(2-Hydroxyethyl)dimethylamine;N,N-Dimethyl-2-aminoethanol;Dimethylmonoethanolamine;N,N-Dimethyl(2-hydroxyethyl)amine;Norcholine;N,N-Dimethyl-N-(β-hydroxyethyl)amine;Dimethyl(hydroxyethyl)amine;Kalpur P;Amietol M 21;N,N-Dimethyl-β-hydroxyethylamine;Dimethol;Texacat DME;Dimethylethanolamine;Rexolin;2-(Dimethylamino)ethyl alcohol;Thancat DME;DMEA;N-(2-Hydroxyethyl)-N,N-dimethylamine;PC CAT DMEA;Dabco DMEA;NSC 2652;Aminoalcohol 2mabs;Jeffcat DMEA;Texacat DMEA;Niax DMEA;Lupragen N 101;Tegoamin DMEA;T 80;N,N-Dimethyl-2-ethanolamine;DeuAdd MA 95;MA 95;Dimethyl MEA;116134-09-9;156681-25-3;1404326-81-3

  • Categories:

    Cosmetic Ingredient  >  Buffering

Description

COLOURLESS LIQUID WITH PUNGENT ODOUR.

2-(Dimethylamino)ethanol Basic Attributes

89.14

89.14

1209235

203-542-8

29221980

Characteristics

23.5

-0.55

Clear colorless to pale yellow Liquid

0.8866 g/cm3 @ Temp: 20 °C

-59 °C

135 °C @ Press: 758 Torr

105 °F

1.433

Micible with water.alcohol: miscible(lit.)

Flammables area

100 mm Hg ( 55 °C)

Relative vapour density (air = 1): 3.03

Oral-Rat LD50: 2000 mg/kg; inhalation-mouse LC50: 3250 mg/m3

In case of fire, high temperature, oxidant is more flammable; high heat produces toxic nitrogen oxide gas

1.4-12.2%(V)

Amine odor

Safety Information

II

8

UN 2051 8/PG 2

1

10-20/21/22-34

25-26-36/37/39-45

KK6125000

C

The warehouse is ventilated, low temperature and dry; stored separately from oxidants and acids

Stable. Flammable. Incompatible with oxidizing agents, copper, copper alloys, zinc, acids, galvanised iron. Hygroscopic.

P261-P280-P305 + P351 + P338-P310

H226-H302 + H312-H314-H331

Toxicity

moderately

2-(Dimethylamino)ethanol Use and Manufacturing

Methods of Manufacturing

1. The ethylene oxide method is obtained by amination of dimethylamine and ethylene oxide through distillation, rectification and dehydration. 2. The chloroethanol method is saponified from chloroethanol and alkali to generate ethylene oxide, and then synthesized with dimethylamine to obtain dimethylaminoethanol. Industrial product dimethylaminoethanol, purity ≥95%. Raw material consumption quota: chloroethanol (32%) 5500kg/t, dimethylamine (40%) 2200kg/t. During production, chloroethanol can also be directly added dropwise to dimethylamine, with a yield of 85%.

Uses

Used as pharmaceutical raw materials, intermediates for the manufacture of dyes, fiber treatment agents, anti-corrosion additives, etc., can be used as water-soluble paint base materials, synthetic resin solvents, etc.; used as dye intermediates, fabric dye assistants and preservatives, and also used Pharmaceutical industry; this product is used in ion exchange resins, polyurethane catalysts, medicine (local anesthetic tetracaine hydrochloride, antihistamines, antispasmodics and antihypertensive drugs, etc.), emulsifiers, textile auxiliaries, corrosion inhibitors, Anti-scaling agent, dye and paint solvent, synthetic 763 resin and its curing agent, etc.; also used as fuel oil additive, as an acrylic acid derivative and used as a flocculant in urban water purification plants. In Japan, 50% of the product is used for ion exchange resins, 13.8% is used for polyurethane catalysts, and coatings account for 11.2%. Used as anti-inhibitors, dye intermediates, fabric dyeing aids, preservatives in the pharmaceutical industry, and resin raw materials.

Computed Properties

Molecular Weight:89.14
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:89.084063974
Monoisotopic Mass:89.084063974
Topological Polar Surface Area:23.5
Heavy Atom Count:6
Complexity:28.7
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Price Analysis

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Drug Function and Efficacy

pH adjuster and buffering agent.

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Registered Holders

  • ABX ADVANCED BIOCHEMICAL COMPOUNDS BIOCHEMISCHE FORSCHUNGSREAGENZIEN GMBH

    United States United States
    Active

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