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5-Sulfoanthranilic acid

5-Sulfoanthranilic acid structure

5-Sulfoanthranilic acid 

structure
  • CAS No:

    3577-63-7

  • Formula:

    C7H7NO5S

  • Chemical Name:

    5-Sulfoanthranilic acid

  • Synonyms:

    Benzoic acid,2-amino-5-sulfo-;Anthranilic acid,5-sulfo-;2-Amino-5-sulfobenzoic acid;4-Sulfo-2-carboxyaniline;4-Amino-3-carboxybenzenesulfonic acid;5-Sulfoanthranilic acid;2-Carboxy-4-sulfoaniline;2-Amino-1-carboxybenzene-5-sulfonic acid

  • Categories:

    Pharmaceutical Intermediates  >  Bulk Drug Intermediates

Description

PHYSICAL DESCRIPTION: Off-pink powder. (NTP, 1992)


5-sulfoanthranilic acid is an off-pink powder. (NTP, 1992)


5-sulfoanthranilic acid is an off-pink powder. (NTP, 1992)

5-Sulfoanthranilic acid Basic Attributes

217.2

217.20

222-697-2

DTXSID2026070

2922499990

Characteristics

126

0.16

5-sulfoanthranilic acid is an off-pink powder. (NTP, 1992)

1.7±0.1 g/cm3

319 °C

1.662

10 to 50 mg/mL at 68.9° F (NTP, 1992)

Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.

Soluble in hot water [Hawley]. Unstable to prolonged exposure to air (NTP, 1992).

Acids, Carboxylic

5-SULFOANTHRANILIC ACID is an amino acid.

Safety Information

P261, P264, P270, P272, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, P501

H302

Flash point data for this material are not available, but it is probably combustible. (NTP, 1992)

|Warning|H302 (33.33%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P272, P280, P301+P312, P302+P352, P305+P351+P338, P321, P330, P332+P313, P333+P313, P337+P313, P362, P363, and P501|Aggregated GHS information provided by 5 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)

SMALL SPILLS AND LEAKAGE: If you spill this chemical, you should dampen the solid spill material with water, then transfer the dampened material to a suitable container. Use absorbent paper dampened with water to pick up any remaining material. Seal your contaminated clothing and the absorbent paper in a vapor-tight plastic bag for eventual disposal. Wash all contaminated surfaces with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should keep this material in a tightly-closed container under an inert atmosphere, and store it at refrigerated temperatures. (NTP, 1992)

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Drug Information

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)

5-Sulfoanthranilic acid Use and Manufacturing

Benzoic acid, 2-amino-5-sulfo-: ACTIVE

Computed Properties

Molecular Weight:217.20
XLogP3:-0.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:217.00449350
Monoisotopic Mass:217.00449350
Topological Polar Surface Area:126
Heavy Atom Count:14
Complexity:320
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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