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Clorprenaline

Clorprenaline structure

CAS No:
3811-25-4
Formula:
C11H16ClNO
Chemical Name:
Clorprenaline
Synonyms:
Benzenemethanol,2-chloro-α-[[(1-methylethyl)amino]methyl]-;Benzyl alcohol,o-chloro-α-[(isopropylamino)methyl]-;2-Chloro-α-[[(1-methylethyl)amino]methyl]benzenemethanol;1-o-Chlorophenyl-2-isopropylaminoethanol;Clorprenaline;Isoprophenamine;E 241;o-Chloro-α-(isopropylaminomethyl)benzyl alcohol;(±)-Chloroprenaline;Isoprofenamine;1-(2-Chlorophenyl)-2-[(propan-2-yl)amino]ethan-1-ol;1-(2-Chlorophenyl)-2-(propan-2-ylamino)ethanol;2-Chloro-α-[(isopropylamino)methyl]benzenemethanol;103125-10-6
Categories:
Active Pharmaceutical Ingredients > Respiratory Drugs

Description

1-(2-chlorophenyl)-2-isopropylaminoethanol is a member of the class of monochlorobenzenes that is chlorobenzene which is substituted by a 1-hydroxy-2-[(propan-2-yl)amino]ethyl group at position 2. It is a member of monochlorobenzenes, a member of ethanolamines and a secondary amino compound.

Clorprenaline Basic Attributes

Molecular Weight：

213.7

Exact Mass：

213.70

EC Number：

223-291-8

DSSTox ID：

DTXSID3048316

HScode：

2922199090

Characteristics

PSA：

32.3

XLogP3：

2.18

Density：

1.1±0.1 g/cm3

Melting Point：

81-82 °C

Boiling Point：

329.7±27.0 °C at 760 mmHg

Flash Point：

153.2±23.7 °C

Refractive Index：

1.537

Collision Cross Section：

146.89 Å² [M+H]+

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

22-36

safety instructions：

Marks：

Precautionary statement(s)：

P305 + P351 + P338

Hazard Statements：

H302-H319

GHS Classification：

|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P280, P301+P312, P305+P351+P338, P330, P337+P313, and P501|Aggregated GHS information provided by 38 companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

MeSH：

Agents that cause an increase in the expansion of a bronchus or bronchial tubes. (See all compounds classified as Bronchodilator Agents.)|Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)

MeSH Entry Terms：

chlorprenaline

Clorprenaline Use and Manufacturing

This product is a selective β2-receptor stimulant and has antispasmodic and relaxing effects on bronchial smooth muscle. It is used to treat bronchial asthma, asthmatic bronchitis, and bronchitis accompanied by emphysema.

Computed Properties

Molecular Weight:213.70
XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:213.0920418
Monoisotopic Mass:213.0920418
Topological Polar Surface Area:32.3
Heavy Atom Count:14
Complexity:163
Undefined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Related Drugs

Compound chlorprenaline and bromhexine capsules
Specifications	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
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Compound chlorprenaline and bromhexine capsules
Specifications	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
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Compound chlorprenaline and bromhexine capsules
Specifications	Chlorprenaline hydrochloride 5mg, bromhexine hydrochloride 10mg, deschlorohydroxyzine hydrochloride 25mg
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