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Safranine

Safranine structure

CAS No:
477-73-6
Formula:
C20H19N4.Cl
Chemical Name:
Safranine
Synonyms:
Phenazinium,3,7-diamino-2,8-dimethyl-5-phenyl-,chloride (1:1);Safranine O;C.I. Basic Red 2;Phenazinium,3,7-diamino-2,8-dimethyl-5-phenyl-,chloride;C.I. 50240;Brilliant Safranine G;Brilliant Safranine BR;Brilliant Safranine GR;Calcozine Red Y;3,7-Diamino-2,8-dimethyl-5-phenylphenazinium chloride;Hidaco Safranine;Leather Red HT;Mitsui Safranine T;Nippon Kagaku Safranine T;Nippon Kagaku Safranine GK;Safranin;Safranin O;Safranine;Safranine GF;Safranine OK;Safranine Superfine G;Safranine TH;Safranine TN;Safranine TS;Safranine YN;Safranine A;Safranine B;Safranine G;Safranine J;Safranine T;Safranine Y;Safranine Zh;2,8-Dimethylphenosafranine;Safranin T;Basic Red 2;Tolusafranine;Gossypimine;Safranine OK 70:100;Duasyn Basic Red TH;Lowacryl Red 2;Lowacryl Red 2 Conc;Basic Pink;Safranin orange;o-Safranin;3,7-Diamino-2,8-dimethyl-5-phenylphenazin-5-ium chloride;74109-45-8
Categories:
Cosmetic Ingredient > Hair Dyeing

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Description

Dark red to violet powder

Safranine Basic Attributes

Molecular Weight：

350.84

Exact Mass：

350.129822

BRN：

3924099

EC Number：

207-518-8

UNII：

XTX0YXU2HV

NSC Number：

47719

DSSTox ID：

DTXSID60103122

HScode：

32041300

Characteristics

PSA：

68.8

XLogP3：

1.61230

Appearance：

S. No.: 967 Solid

Density：

1.00 g/mL at 20 °C

Melting Point：

>240℃ (decompose)

Flash Point：

46 °C

Refractive Index：

n20/D 1.339

Water Solubility：

H2O: soluble 1mg/mL

Storage Conditions：

Store at RT.

Toxicity：

Intravenous-rat LD50: 28.74 mg/kg; Oral-mouse LD50: 1600 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxides and chloride fumes

Experimental Properties：

CATIONIC

Safety Information

Packing level：

Ⅲ

Transport codes：

UN 1170 3/PG 3

wgk germany：

hazard class code：

41-36/38-37/38-10-36/37/38

safety instructions：

26-39-24/25-36-16

RTECS Number：

SG1623000

Marks：

Storage features：

Warehouse ventilated, low temperature and dry

Stability/Shelf Life：

Stable.

Precautionary statement(s)：

P280-P305 + P351 + P338

Hazard Statements：

H318

Toxicity

Toxicity class：

moderately toxic

Drug Information

MeSH：

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS. (See all compounds classified as Coloring Agents.)|Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant and Hackh's Chemical Dictionary, 5th ed, p301, p499) (See all compounds classified as Indicators and Reagents.)

Absorption：

...CATIONIC DYES PENETRATE INTO CELLS & STAIN CELL NUCLEI MORE READILY THAN DO ANIONIC DYES.

Antidote：

...BEST THAT CAN BE OFFERED FOR IMMEDIATE TREATMENT OF EYES CONTAMINATED WITH CATIONIC DYES IS COPIOUS IRRIGATION & METICULOUS MECHANICAL OR SURGICAL REMOVAL OF ALL PARTICLES. IRRIGATION WITH WATER OR SALINE SOLN IS RECOMMENDED...

Human Toxicity Excerpts：

SAFRANIN O...INJURIOUS TO...HUMAN EYE.

MeSH Entry Terms：

Basic Red 2

Safranine Use and Manufacturing

Methods of Manufacturing

Using 2, 5-diaminotoluene, o-toluidine and aniline as raw materials, firstly equimolar 2, 5-diaminotoluene and o-toluidine are oxidized, and then condensed with aniline, and obtained by refining crystals and converting them into chlorides Finished product.

Uses

Used as a reagent for trace analysis of nitrous acid, redox indicator, acid-base indicator, biological stain

Manufacturing Info：

Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-, chloride (1:1): ACTIVE|Phenazinium, 3,7-diamino-2,8-dimethyl-5-phenyl-, chloride (1:1), homopolymer: ACTIVE|XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).|COSMETIC PREPARATIONS--LIPSTICKS MAY CONTAIN SAFRANIN /FROM TABLE/

Use Classification：

Cosmetics -> Hair dyeing

Computed Properties

Molecular Weight:350.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:350.1298243
Monoisotopic Mass:350.1298243
Topological Polar Surface Area:68.8
Heavy Atom Count:25
Complexity:405
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

Material

o-Toluidine

Recommended Suppliers of Safranine

Guangzhou Yaoguang Technology Co., Ltd. Contact Supplier

CN
5 YRS

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Manufactory Supplier of Custom Synthetic Chemicals,Biological Stains,Pharmaceutical Intermediates,Cosmetic Grade Chemicals,Enzyme,Nucleosides,Indicators,Speciality Chemicals,Biological Chemicals,Enzyme Substrates

477-73-6

CAS No.: 477-73-6

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HANGZHOU LEAP CHEM CO., LTD. Contact Supplier

CN
5 YRS

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Trader Supplier of Intermediates,Building blocks,API,Silicones,Peptides,Lab chemicals,Biochemicals,Pharmaceuticals,Screening Compounds,Food Additives

Basic Red 2

CAS No.: 477-73-6

Content: 99.00%

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Henan Lihao Chem Plant Limited Contact Supplier

CN
5 YRS

Business licensed

Trader Supplier of PVC resin,pvc paste resin,melamine

Safranine T 99% see COA kanbei

CAS No.: 477-73-6

Grade: Industrial Grade

Content: 99%

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IN
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SAFRANINE O 477-73-6

CAS No.: 477-73-6

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Guide of Safranine

Description
Basic Attributes
Characteristics
Safety Information
Toxicity
Drug Information
Use and Manufacturing
Computed Properties
Material
Recommended Suppliers
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Safranine

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