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2-Hydroxybenzyl alcohol

2-Hydroxybenzyl alcohol structure

CAS No:
90-01-7
Formula:
C7H8O2
Chemical Name:
2-Hydroxybenzyl alcohol
Synonyms:
,2-Dihydroxytoluene;2-hydroxybenzyl alcool;2-Monomethylol phenol;Salicyl alcohol~Saligenin;2-Hydroxy Benzyl Alcohol o-Hydroxy Benzyl Alcohol;2-Hydroxybenzylalcohol,99%;MONOMETHYLOLPHENOL;SALICYL ALCOHOL(RG)
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Salicyl alcohol is an intermediate for medicine, perfume, pesticide.

Solid

Salicyl alcohol is a hydroxybenzyl alcohol that is phenol substituted by a hydroxymethyl group at C-2. It has a role as a human urinary metabolite. It is an aromatic primary alcohol and a hydroxybenzyl alcohol. It derives from a phenol and a benzyl alcohol.

light brown crystalline powder

Salicyl alcohol: (saligenin, o-hydroxy benzyl alcohol) crystallizes from water in the form of needles or white rhombic crystals. It occurs in nature as the bitter glycoside, salicin CAS: 138-52-3, which is isolated from the bark of Salix helix, S. pentandra, S. praecos, some other species of willow trees, and the bark of a number of species of poplar trees such as Polpulus balsamifera, P. candicans, and P. nigra.

2-Hydroxybenzyl alcohol Basic Attributes

Molecular Weight：

124.14

Exact Mass：

124.14

BRN：

1907195

EC Number：

201-960-5

UNII：

FA1N0842KB

NSC Number：

757317|3814

TSCA：

TSCA listed

DSSTox ID：

DTXSID9045843

Color/Form：

Light beige

HScode：

29072900

Characteristics

PSA：

40.46000

XLogP3：

0.7

Appearance：

Solid

Density：

1,613 g/cm3

Melting Point：

83-85 °C(lit.)

Boiling Point：

190.92°C (rough estimate)

Flash Point：

115.2±12.8 °C

Refractive Index：

1.5035 (estimate)

Water Solubility：

67 g/L (22 ºC)

PKA：

pK1:9.92 (25°C)

Critical Temperature & Pressure：

Store below +30°C.

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

hazard class code：

safety instructions：

26-36

RTECS Number：

DO6430000

Marks：

Xi:Irritant

Stability/Shelf Life：

Stable. Incompatible with acids, acid chlorides, acid anhydrides, strong oxidizing agents.

Precautionary statement(s)：

P261-P305 + P351 + P338

Hazard Statements：

36/37/38

GHS Classification：

|Warning|H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 100 companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Exposure Prevention：

Methylol phenols are sensitizers contained in resins based on phenol and formaldehyde of the resol type. Cross-reactivity is possible with other phenol derivative molecules.

Drug Information

MeSH Entry Terms：

2-methylol phenol

2-Hydroxybenzyl alcohol Use and Manufacturing

Uses

2-Monomethylol phenol is an intermediate in the production of phenol formaldehyde res ins (may remain after condensation of the resin); sensitizer in phenol-formaldehyde resins; in loeal anesthetics. anesthetic (local), antiinflammatory 2-Hydroxybenzyl Alcohol is a phenolic component of a part of a salix bark extract which maintains a minor anti-depressant effect. Phenolic analog with potential for anti-melanomic effect

anesthetic (local), antiinflammatory

Manufacturing Info：

Benzenemethanol, 2-hydroxy-: ACTIVE

Computed Properties

Molecular Weight:124.14
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:124.052429494
Monoisotopic Mass:124.052429494
Topological Polar Surface Area:40.5
Heavy Atom Count:9
Complexity:83
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of 2-Hydroxybenzyl alcohol

Qingdao Orient Chemical Co.,LTD Contact Supplier

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2-Hydroxybenzyl alcohol 90-01-7

CAS No.: 90-01-7

Grade: Industrail Grade

Content: 99%

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Hangzhou KieRay Chem Co.,LTD Contact Supplier

CN
5 YRS

Business licensed Certified factory

Manufactory Supplier of fine chemicals,pharmaceutical materials

2-Hydroxybenzyl alcohol

CAS No.: 90-01-7

Grade: industrial Grade

Content: 98%

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