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Home > Encyclopedia > 1-(17-Methoxyaspidospermidin-1-yl)ethanone

1-(17-Methoxyaspidospermidin-1-yl)ethanone

1-(17-Methoxyaspidospermidin-1-yl)ethanone structure

1-(17-Methoxyaspidospermidin-1-yl)ethanone 

structure
  • CAS No:

    466-49-9

  • Formula:

    C22H30N2O2

  • Chemical Name:

    1-(17-Methoxyaspidospermidin-1-yl)ethanone

  • Synonyms:

    Ethanone,1-(17-methoxyaspidospermidin-1-yl)-;Aspidospermidine,1-acetyl-17-methoxy-;Aspidospermine;1-(17-Methoxyaspidospermidin-1-yl)ethanone;Aspidospermin;(-)-Aspidospermine;NSC 19508;NSC 61811;1405-11-4;28645-74-1

Description

White to brownish-yellow crystalline alkaloid. Soluble in fats, fixed oils, absolute alcohol, and ether. Its sulfate and hydrochloride are soluble in water.


Solid


Aspidospermine is an indole alkaloid having the structure of aspirospermidine methoxylated at C-17 and acetylated at N-1. It derives from a hydride of an aspidospermidine.

1-(17-Methoxyaspidospermidin-1-yl)ethanone Basic Attributes

354.49

354.49

207-376-7

U1475W62Q5

61811|19508

DTXSID70196883

Characteristics

32.8

3.72930

Solid

1.2 g/cm3

208 °C

220 °C

282.1ºC

1.613

166.6mg/L(cold water)

Peritoneal-mouse LD50: 40 mg/kg

Flammable; burning produces toxic nitrogen oxide fumes

D15 -100.2° (alc); D -93° (chloroform)

Safety Information

Ventilated, low temperature and dry; stored separately from food materials in warehouse

Toxicity

highly toxic

Drug Information

aspidospermine

1-(17-Methoxyaspidospermidin-1-yl)ethanone Use and Manufacturing

Medicine (respiratory stimulant).

Computed Properties

Molecular Weight:354.5
XLogP3:3.4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:354.230728204
Monoisotopic Mass:354.230728204
Topological Polar Surface Area:32.8
Heavy Atom Count:26
Complexity:595
Defined Atom Stereocenter Count:4
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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