Corosolic acid
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Corosolic acid
structure -
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CAS No:
4547-24-4
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Formula:
C30H48O4
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Chemical Name:
Corosolic acid
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Synonyms:
Urs-12-en-28-oic acid,2,3-dihydroxy-,(2α,3β)-;Urs-12-en-28-oic acid,2α,3β-dihydroxy-;(2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid;2α-Hydroxyursolic acid;2α,3β-Dihydroxyurs-12-en-28-oic acid;Corosolic acid;Corsolic acid;Glucosol;Colosic acid;Colosolic acid;2α,3β-Dihydroxy ursolic acid;2alpha-Hydroxyursolic acid;2α,2β,-Dihydroxy-12-en-28-ursolic acid;2α,3β-Dihydroxylursolic acid;106327-63-3
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CAS No:
Description
Corosolic acid isolated from the fruit of Cratoegus pinnatifida var. psilosa, was reported to have anticancer activity.IC50 value: 26.8 μg/ml in vitroTarget:In vitro: Corosolic acid displayed about the same potent cytotoxic activity as ursolic acid against several human cancer cell lines. In addition, the compound displayed antagonistic activity against the phorbol ester-induced morphological modification of K-562 leukemic cells, indicating the suppression of protein kinase C (PKC) activ
Characteristics
77.8
7.82
Fine-Brown Yellow Powder
1.1±0.1 g/cm3
283-285 °C @ Solvent: Methanol
573.3±50.0 °C at 760 mmHg
314.6±26.6 °C
1.567
methanol: soluble 1mg/mL, clear, colorless
2-8°C
Corosolic acid Use and Manufacturing
(2α,3β)-2,3-Dihydroxy-urs-12-en-28-oic Acid influences inflammatory gene expression regarding inflammatory bowel disease. In addition, its extracted from the plants Gentiana farreri and shows anti-tumor activity
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