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N-FORMYL-L-METHIONINE

N-FORMYL-L-METHIONINE structure

CAS No:
4289-98-9
Formula:
C6H11NO3S
Chemical Name:
N-FORMYL-L-METHIONINE
Synonyms:
For-L-Met-OH;Formyl-L-methionine≥ 98% (HPLC);n-formylmethionine;FOR-MET-OH;FOR-METHIONINE;FORMYL-L-METHIONINE;FMET;Formylmethionine
Categories:
Biochemical Engineering > Amino Acids and Derivatives

Description

White powder

Solid

N-formyl-L-methionine is a L-methionine derivative in which one of the hydrogens attached to the nitrogen is replaced by a formyl group. It has a role as a metabolite. It is a proteinogenic amino acid, a N-formyl amino acid and a L-methionine derivative. It is a conjugate acid of a N-formyl-L-methioninate.|N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.|Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

ChEBI: A L-methionine derivative in which one of the hydrogens attached to the nitrogen is replaced by a formyl group.

N-FORMYL-L-METHIONINE Basic Attributes

Molecular Weight：

177.22

Exact Mass：

177.22

EC Number：

224-322-8

UNII：

PS9357B4XH

Color/Form：

White to Almost white

HScode：

29304000

Characteristics

PSA：

91.7

XLogP3：

0.44

Appearance：

Solid

Density：

1.242±0.06 g/cm3(Predicted)

Melting Point：

101 °C

Boiling Point：

453.5±40.0 °C(Predicted)

Flash Point：

228.1±27.3 °C

Refractive Index：

-10 ° (C=0.8, H2O)

Water Solubility：

almost transparency in hot Water

Storage Conditions：

−20°C

PKA：

3.32±0.10(Predicted)

Collision Cross Section：

134.09 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|149.53 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|140.73 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|145.3 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.3 Å² [M-H]-

Critical Temperature & Pressure：

−20°C

Safety Information

Transport codes：

NONH for all modes of transport

wgk germany：

safety instructions：

24/25

Drug Information

MeSH Entry Terms：

Formylmethionine, N

N-FORMYL-L-METHIONINE Use and Manufacturing

N-Formyl-L-methionine (fMet) is used to identify, differentiate and characterize amino acid N-deformylase(s), N-carbamoylase(s) and N-aminoacylase(s).

Computed Properties

Molecular Weight:177.22
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:177.04596439
Monoisotopic Mass:177.04596439
Topological Polar Surface Area:91.7
Heavy Atom Count:11
Complexity:140
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 4289-98-9

Grade: Research and Industrial Grade

Content: 98.00%

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CAS No.: 4289-98-9

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Guide of N-FORMYL-L-METHIONINE

Description
Basic Attributes
Characteristics
Safety Information
Drug Information
Use and Manufacturing
Computed Properties
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