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Home > Encyclopedia > N-Formylmethionine

N-Formylmethionine

N-Formylmethionine structure

N-Formylmethionine 

structure
  • CAS No:

    4289-98-9

  • Formula:

    C6H11NO3S

  • Chemical Name:

    N-Formylmethionine

  • Synonyms:

    L-Methionine,N-formyl-;Methionine,N-formyl-,L-;N-Formyl-L-methionine;N-Formylmethionine;Formylmethionine;L-N-Formylmethionine;Formyl-L-methionine;L-Formylmethionine;NSC 334322;(2S)-2-Formamido-4-(methylsulfanyl)butanoic acid;1313606-19-7

  • Categories:

    Biochemical Engineering  >  Amino Acids and Derivatives

Description

White powder


Solid


N-formyl-L-methionine is a L-methionine derivative in which one of the hydrogens attached to the nitrogen is replaced by a formyl group. It has a role as a metabolite. It is a proteinogenic amino acid, a N-formyl amino acid and a L-methionine derivative. It is a conjugate acid of a N-formyl-L-methioninate.|N-Formylmethionine is effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.|Effective in the initiation of protein synthesis. The initiating methionine residue enters the ribosome as N-formylmethionyl tRNA. This process occurs in Escherichia coli and other bacteria as well as in the mitochondria of eucaryotic cells.

N-Formylmethionine Basic Attributes

177.22

177.22

224-322-8

PS9357B4XH

2930909090

Characteristics

91.7

0.44

Solid

1.2±0.1 g/cm3

100.0-101.5 °C

453.5±40.0 °C at 760 mmHg

228.1±27.3 °C

1.517

−20°C

134.09 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|149.53 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|140.73 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|145.3 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.1 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.3 Ų [M-H]-

Safety Information

NONH for all modes of transport

3

24/25

Drug Information

Formylmethionine, N

Computed Properties

Molecular Weight:177.22
XLogP3:0.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:177.04596439
Monoisotopic Mass:177.04596439
Topological Polar Surface Area:91.7
Heavy Atom Count:11
Complexity:140
Defined Atom Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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