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Norwogonin

Norwogonin structure

CAS No:
4443-09-8
Formula:
C15H10O5
Chemical Name:
Norwogonin
Synonyms:
4H-1-Benzopyran-4-one,5,7,8-trihydroxy-2-phenyl-;Flavone,5,7,8-trihydroxy-;5,7,8-Trihydroxy-2-phenyl-4H-1-benzopyran-4-one;Norwogonin;5,7,8-Trihydroxyflavone;NSC 128304
Categories:
Pharmaceutical Intermediates > Bulk Drug Intermediates

Description

Norwogonin, isolated from Scutellaria baicalensis Georgi, possesses antiviral activity against Enterovirus 71 (EV71) with an IC50 of 31.83 μg/ml[1]

Norwogonin is a trihydroxyflavone with the hydroxy groups at positions C-5, -7 and -8. It has a role as an antioxidant and a metabolite.

Norwogonin Basic Attributes

Molecular Weight：

270.24

Exact Mass：

270.24

UNII：

70U0WT21IB

NSC Number：

128304

DSSTox ID：

DTXSID20196171

HScode：

2914400090

Characteristics

PSA：

XLogP3：

2.57680

Density：

1.548g/cm3

Melting Point：

227-228 °C

Boiling Point：

528.4ºC at 760 mmHg

Flash Point：

206ºC

Refractive Index：

1.732

Water Solubility：

H2O: Very slightly soluble (0.26 g/L) (25 ºC)

Drug Information

MeSH Entry Terms：

5,7,8-hydroxyflavone

Norwogonin Use and Manufacturing

Use Classification：

Polyketides [PK] -> Flavonoids [PK12] -> Flavones and Flavonols [PK1211]

Computed Properties

Molecular Weight:270.24
XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:270.05282342
Monoisotopic Mass:270.05282342
Topological Polar Surface Area:87
Heavy Atom Count:20
Complexity:413
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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CAS No.: 4443-09-8

Grade: Industrial Grade

Content: 99%

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