α-Methylcinnamaldehyde
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α-Methylcinnamaldehyde
structure -
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CAS No:
101-39-3
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Formula:
C10H10O
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Chemical Name:
α-Methylcinnamaldehyde
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Synonyms:
2-Propenal,2-methyl-3-phenyl-;Cinnamaldehyde,α-methyl-;2-Methyl-3-phenyl-2-propenal;α-Methylcinnamaldehyde;α-Methylcinnamic aldehyde;2-Methyl-3-phenylacrolein;2-Methyl-3-phenylacrylaldehyde;NSC 22283;NSC 49286;2-Methylcinnamic aldehyde;2-Methyl-3-phenylpropenal;Methylcinnamaldehyde;2-Methyl-3-phenyl-2-propen-1-al
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CAS No:
Description
α-Methylcinnamaldehyde has a characteristic cinnamon-type odor and a soft, spicy flavor. yellow liquidα-Methylcinnamaldehyde has a characteristic cinnamon-type odor with a soft, spicy flavor. May be synthesized by condensing benzaldehyde with propionic aldehyde in the presence of a 1% caustic soda solution; also by the controlled hydrogenation of α-methylcinnamic aldehyde.Clear yellow liquid.
Alpha-methylcinnamaldehyde is a clear yellow liquid. (NTP, 1992)|Liquid|Yellow liquid, cinnamon-like odour
Alpha-methylcinnamaldehyde is a clear yellow liquid. (NTP, 1992)
Characteristics
17.1
2.28880
Alpha-methylcinnamaldehyde is a clear yellow liquid. (NTP, 1992)
1.0538 g/cm3 @ Temp: 20 °C
251.6 °C
175 °F
n 20/D 1.605(lit.)
<0.1 g/100 mL at 21 ºC Insoluble in water.
Store below +30°C.
0.02 mmHg
Insoluble in water.
Aldehydes
ALPHA-METHYLCINNAMALDEHYDE is incompatible with strong oxidizing agents and strong bases. (NTP, 1992)
Safety Information
1
36/37/38
24/25
GD6600000
Xi
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
This chemical is combustible. (NTP, 1992)
|Warning|H317 (99.66%): May cause an allergic skin reaction [Warning Sensitization, Skin]|P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501|Aggregated GHS information provided by 1783 companies from 6 notifications to the ECHA C&L Inventory.
Fires involving this material should be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Excerpt from ERG Guide 128 [Flammable Liquids (Water-Immiscible)]: As an immediate precautionary measure, isolate spill or leak area for at least 50 meters (150 feet) in all directions. LARGE SPILL: Consider initial downwind evacuation for at least 300 meters (1000 feet). FIRE: If tank, rail car or tank truck is involved in a fire, ISOLATE for 800 meters (1/2 mile) in all directions; also, consider initial evacuation for 800 meters (1/2 mile) in all directions. (ERG, 2016)
SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. STORAGE PRECAUTIONS: You should store this chemical under refrigerated temperatures, and keep it away from oxidizing materials. STORE AWAY FROM SOURCES OF IGNITION. (NTP, 1992)
RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Drug Information
SYMPTOMS: This compound causes irritation on contact. ACUTE/CHRONIC HAZARDS: This compound may cause irritation on contact. When heated to decomposition it emits toxic fumes. (NTP, 1992)
EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment. INHALATION: IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. If symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop, call a physician and be prepared to transport the victim to a hospital. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used; if not available, use a level of protection greater than or equal to that advised under Protective Clothing. INGESTION: DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
α-Methylcinnamaldehyde Use and Manufacturing
It is formed by condensation of benzaldehyde and propionaldehyde in 1% caustic soda aqueous solution.
Organic and pharmaceutical synthesis intermediates can be used to synthesize a variety of drugs, such as epalrestat.
Flavor and Fragrance
Air care products
100,000 - 500,000 lb
All other basic organic chemical manufacturing|2-Propenal, 2-methyl-3-phenyl-: ACTIVE
Food additives -> Flavoring Agents|Flavoring Agents -> JECFA Flavorings Index
Flavoring Agents
Computed Properties
Molecular Weight:146.19
XLogP3:2.2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:146.073164938
Monoisotopic Mass:146.073164938
Topological Polar Surface Area:17.1
Heavy Atom Count:11
Complexity:152
Undefined Bond Stereocenter Count:1
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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