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Kanamycin B

Kanamycin B structure

CAS No:
4696-76-8
Formula:
C18H37N5O10
Chemical Name:
Kanamycin B
Synonyms:
D-Streptamine,O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-;Kanamycin B;O-3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine;Kanendomycin;Aminodeoxykanamycin;2′-Amino-2′-deoxykanamycin;Bekanamycin;KDM;NK 1006;Nebramycin V;Nebramycin factor 5;Beckanamycin;25100-46-3;37321-11-2
Categories:
Active Pharmaceutical Ingredients > Antibiotics

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Description

Bekanamycin is an aminoglycoside antibiotic.

Kanamycin B Basic Attributes

Molecular Weight：

483.51

Exact Mass：

483.51

EC Number：

225-170-5

DSSTox ID：

DTXSID8023185

Characteristics

PSA：

288

Density：

1.6±0.1 g/cm3

Melting Point：

178-182 °C (decomp)

Boiling Point：

807.7°C at 760 mmHg

Flash Point：

442.3±34.3 °C

Refractive Index：

1.668

Toxicity：

Peritoneal-mouse LD50: 800 mg/kg; subcutaneous-mouse LD50: 750 mg/kg

Flammability characteristics：

Flammable; burning produces toxic nitrogen oxide fumes

Specific rotation：

D18 +130° (c = 0.5 in water); D21 +114° (c = 0.98 in water)

Safety Information

Storage features：

Ventilated, low temperature and dry

Toxicity

Toxicity class：

moderately toxic

Kanamycin B Use and Manufacturing

It is an antibiotic and an intermediate for the production of dibekacin sulfate and arbekacin sulfate

Computed Properties

Molecular Weight:483.5
XLogP3:-7.2
Hydrogen Bond Donor Count:11
Hydrogen Bond Acceptor Count:15
Rotatable Bond Count:6
Exact Mass:483.25404239
Monoisotopic Mass:483.25404239
Topological Polar Surface Area:288
Heavy Atom Count:33
Complexity:639
Undefined Atom Stereocenter Count:15
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

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