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Spermidine

pharmaceutical raw materials
Spermidine structure

Spermidine 

structure
  • CAS No:

    124-20-9

  • Formula:

    C7H19N3

  • Chemical Name:

    Spermidine

  • Synonyms:

    1,4-Butanediamine,N1-(3-aminopropyl)-;Spermidine;1,4-Butanediamine,N-(3-aminopropyl)-;N1-(3-Aminopropyl)-1,4-butanediamine;4-Azaoctane-1,8-diamine;Spermidin;N-(4-Aminobutyl)-1,3-diaminopropane;1,5,10-Triazadecane;N-(3-Aminopropyl)-1,4-butanediamine;N-(3-Aminopropyl)-4-aminobutylamine;N-(3-Aminopropyl)-1,4-diaminobutane;1,8-Diamino-4-azaoctane;(4-Aminobutyl)(3-aminopropyl)amine

  • Categories:

    Cosmetic Ingredient  >  Antioxidant Ingredient

Description

Colorless clear liquidChEBI: A triamine that is the 1,5,10-triaza derivative of decane.


Solid


Spermidine is a triamine that is the 1,5,10-triaza derivative of decane. It has a role as a fundamental metabolite. It is a triamine and a polyazaalkane. It is a conjugate base of a spermidine(3+).|Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.|Spermidine is a polyamine derived from putrescine that is involved in many biological processes, including the regulation of membrane potential, the inhibition of nitric oxide synthase (NOS) and the induction of autophagy.|A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.

Spermidine Basic Attributes

145.25

145.25

1698591

204-689-0

U87FK77H25

DTXSID4036645

C129012

29212900

Characteristics

64.1

-0.84

Clear colorless Liquid After Melting

1.00 g/mL at 20 °C

<25 °C

129 °C

>230 °F

n 20/D 1.479(lit.)

Miscible with water, ethanol and ether.

2-8°C

0.0269mmHg at 25°C

131.9 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|131.4 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|131.6 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.1 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.5 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|131.3 Ų [M+H]+

Safety Information

III

8

UN 2735 8/PG 2

3

34

26-36/37/39-45-27

EJ7000000

C

Stable, but air-sensitive and very hygroscopic - store under argon. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.

P280-P305 + P351 + P338-P310

H314

|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501|Aggregated GHS information provided by 194 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Drug Information

Spermidine

Spermidine Use and Manufacturing

Uses

Spermidine is a biogenic polyamine formed from putrescine. Spermidine is a precursor of Spermine. Spermidine is essential for both normal and neoplastic tissue growth.

1,4-Butanediamine, N1-(3-aminopropyl)-: ACTIVE

Computed Properties

Molecular Weight:145.25
XLogP3:-1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:145.157897619
Monoisotopic Mass:145.157897619
Topological Polar Surface Area:64.1
Heavy Atom Count:10
Complexity:56.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Material

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