Spermidine
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Spermidine
structure -
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CAS No:
124-20-9
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Formula:
C7H19N3
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Chemical Name:
Spermidine
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Synonyms:
1,4-Butanediamine,N1-(3-aminopropyl)-;Spermidine;1,4-Butanediamine,N-(3-aminopropyl)-;N1-(3-Aminopropyl)-1,4-butanediamine;4-Azaoctane-1,8-diamine;Spermidin;N-(4-Aminobutyl)-1,3-diaminopropane;1,5,10-Triazadecane;N-(3-Aminopropyl)-1,4-butanediamine;N-(3-Aminopropyl)-4-aminobutylamine;N-(3-Aminopropyl)-1,4-diaminobutane;1,8-Diamino-4-azaoctane;(4-Aminobutyl)(3-aminopropyl)amine
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CAS No:
Description
Colorless clear liquidChEBI: A triamine that is the 1,5,10-triaza derivative of decane.
Solid
Spermidine is a triamine that is the 1,5,10-triaza derivative of decane. It has a role as a fundamental metabolite. It is a triamine and a polyazaalkane. It is a conjugate base of a spermidine(3+).|Spermidine is a polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.|Spermidine is a polyamine derived from putrescine that is involved in many biological processes, including the regulation of membrane potential, the inhibition of nitric oxide synthase (NOS) and the induction of autophagy.|A polyamine formed from putrescine. It is found in almost all tissues in association with nucleic acids. It is found as a cation at all pH values, and is thought to help stabilize some membranes and nucleic acid structures. It is a precursor of spermine.
Spermidine Basic Attributes
145.25
145.25
1698591
204-689-0
U87FK77H25
DTXSID4036645
C129012
29212900
Characteristics
64.1
-0.84
Clear colorless Liquid After Melting
1.00 g/mL at 20 °C
<25 °C
129 °C
>230 °F
n 20/D 1.479(lit.)
Miscible with water, ethanol and ether.
2-8°C
0.0269mmHg at 25°C
131.9 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|131.4 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|131.6 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.1 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|136.5 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|131.3 Ų [M+H]+
Safety Information
III
8
UN 2735 8/PG 2
3
34
26-36/37/39-45-27
EJ7000000
C
Stable, but air-sensitive and very hygroscopic - store under argon. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
P280-P305 + P351 + P338-P310
H314
|Danger|H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]|P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501|Aggregated GHS information provided by 194 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Spermidine Use and Manufacturing
Spermidine is a biogenic polyamine formed from putrescine. Spermidine is a precursor of Spermine. Spermidine is essential for both normal and neoplastic tissue growth.
1,4-Butanediamine, N1-(3-aminopropyl)-: ACTIVE
Computed Properties
Molecular Weight:145.25
XLogP3:-1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:145.157897619
Monoisotopic Mass:145.157897619
Topological Polar Surface Area:64.1
Heavy Atom Count:10
Complexity:56.8
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
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