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4-Aminophenol hydrochloride

4-Aminophenol hydrochloride structure

4-Aminophenol hydrochloride 

structure
  • CAS No:

    51-78-5

  • Formula:

    C6H7NO.ClH

  • Chemical Name:

    4-Aminophenol hydrochloride

  • Synonyms:

    Phenol,4-amino-,hydrochloride (1:1);Phenol,p-amino-,hydrochloride;Phenol,4-amino-,hydrochloride;C.I. 76551;p-Aminophenol hydrochloride;C.I. Oxidation Base 6A;Durafur Brown R;Fouramine CP;Fourrine P;Fourrine 83;Furro P;Futramine P;Pelagol CP;Pelagol Grey CP;Peltol P;4-Aminophenol hydrochloride;4-Hydroxyanilinium chloride;p-Hydroxyaniline hydrochloride

  • Categories:

    Cosmetic Ingredient  >  Hair Dyeing

Description

Off white powder

4-Aminophenol hydrochloride Basic Attributes

145.59

145.02900

200-122-6

IWL2N22RFY

DTXSID6058760

Crystalline powder

29222900

Characteristics

46.25000

2.35760

gray powder

1.21g/cm3

306 °C (decomp)

282ºC at 760mmHg

124.3ºC

H2O: soluble

Store below +30°C.

Peritoneal-mouse LD50: 750 mg/kg

Open flames are flammable; heated to decompose toxic nitrogen oxides and chloride gases

Gradually becomes darker; decomp about 306 °C

Safety Information

I; II; III

6.1

NONH for all modes of transport

3

36/37/38-43

28-36

SJ6070000

Xi

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Stable, but hygroscopic, air and light sensitive. Incompatible with strong oxidizing agents.

P261-P280-P305 + P351 + P338

H315-H317-H319-H335

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

|Warning|H315 (92.86%): Causes skin irritation [Warning Skin corrosion/irritation]|P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501|Aggregated GHS information provided by 42 companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.|H302: Harmful if swallowed [Warning Acute toxicity, oral]|P201, P202, P260, P261, P264, P270, P271, P272, P280, P281, P301+P312, P302+P352, P304+P312, P304+P340, P308+P313, P312, P314, P321, P330, P333+P313, P363, P405, and P501

Personnel protection: ... Wear positive pressure self-contained breathing apparatus. ... Wear appropriate chemical protective clothing. /Aminophenols/

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Use water in flooding quantities as fog. Use foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources. /Aminophenols/

If material not on fire and not involved in fire: Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. /Aminophenols/|Personnel protection: Avoid breathing dusts, and fumes from burning material. Keep upwind. ... Avoid bodily contact with the material. ... Do not handle broken packages unless wearing appropriate personal protective equipment. /Aminophenols/

Toxicity

moderately toxic

LD50 Mouse Intraperitoneal 750 mg/kg

Drug Information

Chemical agents that increase the rate of genetic mutation by interfering with the function of nucleic acids. A clastogen is a specific mutagen that causes breaks in chromosomes. (See all compounds classified as Mutagens.)

9. IF...SPILLED ON CLOTHING, REMOVE IMMEDIATELY & DISCARD. ANY CONTAMINATED AREA OF SKIN SHOULD BE WASHED FOR 10 TO 15 MIN WITH SOAP & RUNNING WATER. ... /ANILINE/|/SRP:/ Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patent can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Aniline and related compounds/|/SRP:/ Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Administer 1% solution methylene blue if patient is symptomatic with severe hypoxia, cyanosis, and cardiac compromise not responding to oxygen. ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Consider vasopressors if hypotensive with a normal fluid volume. Watch for signs of fluid overload ... . Treat seizures with diazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Aniline and related compounds/

MAY CAUSE SKIN SENSITIZATION, DERMATITIS. INHALATION CAN CAUSE ASTHMA, METHEMOGLOBIN FORMATION. /P-AMINOPHENOL/

4-aminophenol

4-Aminophenol hydrochloride Use and Manufacturing

Uses

Mainly used for fur dyeing brown, also can be used as sulfur dyes and pharmaceutical intermediates. Take pictures

Phenol, 4-amino-, hydrochloride (1:1): INACTIVE

Cosmetics -> Hair dyeing

Computed Properties

Molecular Weight:145.59
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Exact Mass:145.0294416
Monoisotopic Mass:145.0294416
Topological Polar Surface Area:46.2
Heavy Atom Count:9
Complexity:66.9
Covalently-Bonded Unit Count:2
Compound Is Canonicalized:Yes

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