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Cellocidin

Cellocidin structure

CAS No:
543-21-5
Formula:
C4H4N2O2
Chemical Name:
Cellocidin
Synonyms:
2-Butynediamide;Acetylenedicarboxamide;Acetylenedicarboxylic acid diamide;Aquamycin;Cellocidin;Lenamycin;Acetylene diamide;NSC 38643;NSC 65381;102489-37-2
Categories:
Chemical Reagents > Organic Reagents

Description

CREAM TO BEIGE FINE CRYSTALLINE POWDER

Cellocidin is a dicarboxylic acid diamide resulting from the formal condensation of both of the carboxy groups of butynedioic acid with ammonia. An antibacterial agent produced by Streptomyces chibaensis. It has a role as an antimicrobial agent, an antibacterial agent, a metabolite and a pesticide. It is a ynamide, a dicarboxylic acid diamide and a primary carboxamide. It derives from a butynedioic acid.

Cellocidin Basic Attributes

Molecular Weight：

112.09

Exact Mass：

112.09

EC Number：

200-816-9

UNII：

1K327HA41T

NSC Number：

65381|38643

DSSTox ID：

DTXSID1060261

HScode：

2924199090

Characteristics

PSA：

86.2

XLogP3：

-1.2

Appearance：

Cream to beige Fine Crystalline Powder

Density：

1.41g/cm3

Melting Point：

217 °C (decomp)

Boiling Point：

294ºC at 760 mmHg

Flash Point：

131.6ºC

Refractive Index：

1.56

Vapor Pressure：

0.00167mmHg at 25°C

Toxicity：

Oral-Mouse LD50: 89.2 mg/kg

Flammability characteristics：

Combustion produces toxic nitrogen oxide gas

Safety Information

hazard class code：

25-21

safety instructions：

45-36/37-28A

Marks：

Storage features：

The warehouse is ventilated, low temperature and dry; stored and transported separately from food materials

Precautionary statement(s)：

P264, P270, P280, P301+P310, P302+P352, P312, P321, P322, P330, P361, P363, P405, P501

Hazard Statements：

H301

GHS Classification：

|Warning|H302 (95%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 40 companies from 3 notifications to the ECHA C&L Inventory.|Danger|H301: Toxic if swallowed [Danger Acute toxicity, oral]|P264, P270, P280, P301+P310, P302+P352, P312, P321, P322, P330, P361, P363, P405, and P501

Toxicity

Toxicity class：

highly toxic

Drug Information

MeSH Entry Terms：

cellocidin

Cellocidin Use and Manufacturing

Uses

Cellocidin is a small neutral alkyne produced by a number of Streptomyces species, first discovered by Suzuki and colleagues in 1958. Cellocidin has a broad antibacterial, antifungal and antitumor profile due to its ability to react with endogenous thiols like cysteine and glutathione. Cellocidin occurs as a weak active in many bioassays using actinomycete crude extracts and is thus a useful standard for chemical and bioassay dereplication.

Manufacturing Info：

2-Butynediamide: INACTIVE

Computed Properties

Molecular Weight:112.09
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Exact Mass:112.027277375
Monoisotopic Mass:112.027277375
Topological Polar Surface Area:86.2
Heavy Atom Count:8
Complexity:165
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Recommended Suppliers of Cellocidin

Shandong Ranhang Biotechnology Co., Ltd. Contact Supplier

CN
3 YRS

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Trader Supplier of chemical

ACETYLENEDICARBOXAMIDE 543-21-5

CAS No.: 543-21-5

Grade: Pharmaceutical Grade

Content: 99%

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