Bisabolol
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Bisabolol
structure -
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CAS No:
515-69-5
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Formula:
C15H26O
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Chemical Name:
Bisabolol
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Synonyms:
3-Cyclohexene-1-methanol,α,4-dimethyl-α-(4-methyl-3-penten-1-yl)-,(αR,1R)-rel-;5-Hepten-2-ol,6-methyl-2-(4-methyl-3-cyclohexen-1-yl)-;3-Cyclohexene-1-methanol,α,4-dimethyl-α-(4-methyl-3-pentenyl)-,(R*,R*)-;3-Cyclohexene-1-methanol,α,4-dimethyl-α-(4-methyl-3-pentenyl)-,(αR,1R)-rel-;rel-(αR,1R)-α,4-Dimethyl-α-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-methanol;α-Bisabolol;Bisabolol;dl-α-Bisabolol;Dragosantol;(±)-α-Bisabolol;Hydagen B;Camilol;Dragosantol 100;21090-60-8;25428-43-7;63601-23-0;67375-41-1
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CAS No:
Description
alpha-Bisabolol is a nontoxic sesquiterpene alcohol present in natural essential oil, with anticancer activity. alpha-Bisabolol exerts selective anticancer effect on A549 NSCLC cells (IC50=15 μM) via induction of cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol also strongly induces apoptosis in glioma cells[1][2].
Characteristics
20.23000
5.07
Liquid
0.9216 g/cm3 @ Temp: 18 °C
<25 °C
156 °C
135°C
1.494
soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water.
Keep tightly closed. Store in a cool dry place.
Oral-rat LD50: 14850 mg/kg; Oral-Mouse LD50:11350 mg/kg
Flammable; burning produces irritating fumes
Safety Information
2
33
MJ9685000
Warehouse ventilated, low temperature and dry
Stable. Combustible. Incompatible with strong oxidizing agents.
Bisabolol Use and Manufacturing
alpha-Bisabolol is a botanical used for its anti-inflammatory and soothing properties. It is derived from chamomile and/or yarrow.
Drug Function and Efficacy
Anti-inflammatory and skin-soothing agent, derived from chamomile, helps calm sensitive skin
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