Rutin
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Rutin
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CAS No:
153-18-4
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Formula:
C27H30O16
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Chemical Name:
Rutin
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Synonyms:
4H-1-Benzopyran-4-one,3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-;Rutin;Ilixanthin;Flavone,3,3′,4′,5,5′,7-hexahydroxy-,(6-O-α-L-rhamnosyl-β-D-glucoside);3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one;C.I. 75730;Birutan;Eldrin;Globulariacitrin;Melin;Myrticalorin;Myrticolorin;Myticolorin;Osyritin;Osyritrin;Oxyritin;3,3′,4′,5,7-Pentahydroxyflavone 3-rutinoside;Phytomelin;Quercetin 3-rutinoside;Rutabion;Rutinic acid;Rutoside;Sophorin;Tanrutin;Violaquercitrin;3-Rutinosylquercetin;Quercetin 3-β-rutinoside;Quercetin 3-O-β-D-rutinoside;Globularicitrin;Paliuroside;Rutosid;Quercetin 3-O-rutinoside;5,7,3′,4′-Tetrahydroxyflavonol-3-O-rutinoside;3,3′,4′,5,7-Pentahydroxyflavone 3-O-rutinoside;Quercetin 3-O-β-rutinoside;Quercetin 3-rhamnoglucoside;Violaquercetrin;Ilixathin;NSC 9220;Quercetin 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside;Rutozid;3-O-Rutinosylquercetin;Novarrutina;Quercetin 3-O-α-rhamnopyranosyl(1→6)-β-glucopyranoside;Yunxianggan;Quercetin 3-O-α-rhamnopyranosyl(1′′→6′)-β-D-glucopyranoside;Rutine;Quercetin 3-O-β-D-(6′′-O-α-L-rhamnopyranosyl)glucopyranoside;Quercetin 3-O-α-L-rhamnopyranosyl-β-D-glucopyranoside;Quercetin rutinoside;Quercetin 3-O-α-rhamnopyranosyl-(1′′′→6′′)-β-glucopyranoside;Quercetin 6-O-α-L-rhamnosyl-β-D-glucoside;1416-01-9;18449-50-8;48197-72-4;56764-99-9;115888-40-9;146525-66-8;158560-09-9;164535-43-7;523994-24-3;1296849-98-3
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CAS No:
Description
Pale-Yellow Crystalline SolidChEBI: A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups.
Solid
Rutin is a rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups. It has a role as a metabolite and an antioxidant. It is a disaccharide derivative, a quercetin O-glucoside, a tetrahydroxyflavone and a rutinoside.|A flavonol glycoside found in many plants, including buckwheat; tobacco; forsythia; hydrangea; viola, etc. It has been used therapeutically to decrease capillary fragility.|A flavonol glycoside found in many plants, including BUCKWHEAT; TOBACCO; FORSYTHIA; HYDRANGEA; VIOLA, etc. It has been used therapeutically to decrease capillary fragility.
Rutin Basic Attributes
610.51700
610.52
205-814-1
5G06TVY3R7
DTXSID3022326
C05CA01|C - Cardiovascular system
2932999099
Characteristics
269.43000
-1.3
Solid
1.82 g/cm3
125 °C
983.1ºC at 760 mmHg
325.4ºC
1.765
H2O: 12.5 g/100 mL
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protect
LD50 i.v. in mice: 950 mg/kg (propylene glycol soln) (Harrison)
232.6 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|231.04 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|236.2 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|251.61 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|235.49 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|234.7 Ų [M-H]-
Safety Information
3
R22
S24/25
VM2975000
Xn; Xi
Stable at room temperature in closed containers under normal storage and handling conditions.
P264, P270, P301+P312, P330, P501
H302
|Warning|H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]|P264, P270, P301+P312, P330, and P501|Aggregated GHS information provided by 39 companies from 1 notifications to the ECHA C&L Inventory.|H302 (61.54%): Harmful if swallowed [Warning Acute toxicity, oral]|P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501|Aggregated GHS information provided by 65 companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Rutin Use and Manufacturing
1. Found in many plants, especially the buckwheat plant. Identity with Ilixanthin. Capillary protectant. Rutin is colored brown by tobacco enzyme under experimental conditions.
2. Antidiabetic, dipeptidyl peptidase鈥? inhibitor
3. For nutritional product
4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-.alpha.-L-mannopyranosyl)-.beta.-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-: ACTIVE
Cosmetics -> Antioxidant; Hair conditioning; Skin conditioning
Computed Properties
Molecular Weight:610.5
XLogP3:-1.3
Hydrogen Bond Donor Count:10
Hydrogen Bond Acceptor Count:16
Rotatable Bond Count:6
Exact Mass:610.15338487
Monoisotopic Mass:610.15338487
Topological Polar Surface Area:266
Heavy Atom Count:43
Complexity:1020
Defined Atom Stereocenter Count:10
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes
Drug Function and Efficacy
It is a glycoside of dehydrogenated flavonoids, which often coexists with vitamin C in food. It may participate in the action of oxidoreductase in the body, affect the activity of the thyroid gland, and protect adrenaline from oxidation, enhance the effect of vitamin C and promote the accumulation of vitamin C in the body, maintain vascular elasticity, enhance capillary resistance, and reduce its fragility and permeability.
Registered Holders
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Sichuan Xieli Pharmaceutical Co., Ltd.
Active
China
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Sichuan Shuzhong Pharmaceutical Co., Ltd.
Active
China
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Shaanxi Huifeng Pharmaceutical Ltd.
Active
China
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