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(-)-Scopolamine methobromide

(-)-Scopolamine methobromide structure

CAS No:
155-41-9
Formula:
C18H24NO4.Br
Chemical Name:
(-)-Scopolamine methobromide
Synonyms:
3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-,bromide (1:1),(1α,2β,4β,5α,7β)-;1αH,5αH-Tropanium,6β,7β-epoxy-3α-hydroxy-8-methyl-,bromide,(-)-tropate;3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9,9-dimethyl-,bromide,[7(S)-(1α,2β,4β,5α,7β)]-;N-Methylscopolammonium bromide;3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9,9-dimethyl-,bromide,(1α,2β,4β,5α,7β)-;Tropic acid,(-),ester with 6β,7β-epoxy-3α-hydroxy-8-methyl-1αH,5αH-tropanium bromide;3-Oxa-9-azatricyclo[3.3.1.02,4]nonane,3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane deriv.;Ampyrox;Blocan;Diopal;Epoxymethamine bromide;Epoxytropine tropate methylbromide;Holopon;Lescopine bromide;Mescopil;Methscopolamine bromide;Methscopolamin bromide;Methylscopolamine bromide;Nutrop;Paraspan;Proscomide;Scopolamine methyl bromide;Hyoscine methyl bromide;Neo-Avagal;Pamine bromide;Restropin;Pamine;(-)-Scopolamine methyl bromide;Scopolamine methobromide;U 5036;Hyoscine methobromide;N-Methylscopolamine bromide;(-)-Scopolamine methobromide;NSC 120606;NSC 61809;N-Methylscopolaminium bromide;1420-31-1;2660-04-0
Categories:
Active Pharmaceutical Ingredients > Digestive System Drugs

Description

Methscopolamine (Pamine) is a muscarinic acetylcholine receptor blocker. Target: mAChRMethylscopolamine is an oral medication used along with other medications to treat peptic ulcers by reducing stomach acid secretion. With the advent of proton pump inhibitors and antihistamine medications it is rarely used for this. It can also be used for stomach or intestinal spasms, to reduce salivation, and to treat motion sickness. From Wikipedia.Methscopolamine (Pamine), an anti-acetylcholine drug

(-)-Scopolamine methobromide Basic Attributes

Molecular Weight：

398.29

Exact Mass：

397.088867

EC Number：

205-844-5

NSC Number：

120606|61809

HScode：

2934999090

Characteristics

PSA：

59.06000

XLogP3：

log Kow = -2.58 (est)

Appearance：

white powder

Melting Point：

214-217 °C (decomp)

Refractive Index：

-24 ° (C=1, H2O)

Water Solubility：

H2O: 50 mg/mL

Vapor Pressure：

1.04X10-14 mm Hg at 25 °C (est)

Odor：

ODORLESS

Safety Information

Packing level：

III

Hazard category：

6.1

Transport codes：

UN 1544 6.1/PG 3

wgk germany：

hazard class code：

23/24/25-50/53-20/21/22-20/21

safety instructions：

36/37/39-45-61-60-36/37

RTECS Number：

YM3675000

Marks：

T,N,Xn

Precautionary statement(s)：

P261-P280

Hazard Statements：

H312 + H332-H400

(-)-Scopolamine methobromide Use and Manufacturing

Uses

Scopolamine Methyl Bromide is the methylated derivative of Scopolamine (S200000), a muscarinic antagonist that is similar to acetylcholine. Scopolamine Methyl Bromide have been used for the treatment of peptic ulcers by reducing acid secretion of the stomach and is used to treat morning sickness.

Use Classification：

Human Drugs -> FDA Approved Drug Products with Therapeutic Equivalence Evaluations (Orange Book) -> Active Ingredients

Computed Properties

Molecular Weight:318.4
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:318.17053325
Monoisotopic Mass:318.17053325
Topological Polar Surface Area:59.1
Heavy Atom Count:23
Formal Charge:1
Complexity:454
Undefined Atom Stereocenter Count:5
Covalently-Bonded Unit Count:1
Compound Is Canonicalized:Yes

Drug Function and Efficacy

Extract from the above information

This ingredient has been used in drugs with the following functions (note: it does not mean that the ingredient itself has the following health functions)

Related Drugs

Scopolamine Bromide
Manufacturer	China Resources Double-Crane Pharmaceutical Co., Ltd.

Scopolamine Bromide Tablets
Ingredients	Scopolamine Methylbromide
Indication	It is not clear yet.
Specifications	1mg
Manufacturer	Guangzhou Baiyunshan Guanghua Pharmaceutical Co., Ltd.

Scopolamine Bromide Tablets
Ingredients	Scopolamine Methylbromide
Indication	It is not clear yet.
Specifications	1mg
Manufacturer	Guangzhou Baiyunshan Guanghua Pharmaceutical Co., Ltd.

See More Related Drugs

Registered Holders

China Resources Double-Crane Pharmaceutical Co., Ltd.

China
Active
Guangzhou Hanfang Pharmaceutical Company Limited

China
Active
PHYTEX AUSTRALIA PVT LTD

United States
Active

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METHSCOPOLAMINE BROMIDE cas 155-41-9

CAS No.: 155-41-9

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cas155-41-9 Methscopolamine (bromide)

CAS No.: 155-41-9

Grade: Pharmaceutical Grade

Content: 99%

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Guide of (-)-Scopolamine methobromide

Description
Basic Attributes
Characteristics
Safety Information
Use and Manufacturing
Computed Properties
Drug Function and Efficacy
Related Drugs
Registered Holders
Recommended Suppliers
Latest News
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(-)-Scopolamine methobromide

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